genetic structure

Gene Expression

Tag archives for genetic structure

A little bit of the Others in Us

Dienekes has reposted some of the abstracts from the meeting of the American Association of Physical Anthropologists. This one caught my eye,

Interesting that I just pointed to Neandertal DNA, a really big story just came out on ancient Greenlander genetics, Whole Genome of Ancient Human Is Decoded: The genome of a man who lived on the western coast of Greenland some 4,000 years ago has been decoded, thanks to the surprisingly good preservation of DNA in…

X chromosome marks the spot, again

A few days ago I discussed a new paper which explores the patterns of natural selection in the genome of the X chromosome. As you know the X is “carried” disproportionately by females, as males have only one copy, so it offers up an interesting window into evolutionary dynamics (see The Red Queen for a…

The origins of the Yakuts

One of the more substantive consequences of the powerful new genomic techniques has been in the area of ancient DNA extraction and analysis. The Neandertal genome story is arguably the sexiest, but closer to the present day there’ve been plenty of results which have changed the way we look at the past. The input of…

How Columbus was not a seer

A week ago I pointed out that in some visualizations of world wide population variation South Asians & mestizos seem to overlap which each other to a great extent. The reason for this is that both populations can be modeled as admixtures between two separate, but related, populations. Mestizos are the products of pairings between…

Are Chinese subsets of Southeast Asians?

That’s probably the big takeaway of a new paper on the genetics of Asians, a set which includes South Asians, but in the new research mostly focuses on the people of East Asia. In a global context this work is important. The backstory is that there are disagreements about the exact process of the “Out…

According to search engine traffic one of the most popular posts on this weblog has to do with the genetic background of Ashkenazi Jews. That is, those Jews whose ancestors derive from Central & Eastern Europe, and the overwhelming number of Jews in the United States. The genetic origins of this group are fraught with…

Same science, different inference

About two weeks ago I pointed to the peculiar disjunction between what a paper on Indian genetics actually said, and how people, including some of the researchers who contributed to the paper, were spinning it. For instance, the finding that South Asians can be reasonably modeled as a two-way admixture between “Ancestral North Indians” (ANI)…

Brazil, the case of triracial white people

One of the problems with human genetics where it resembles economics are the ethical issues involved in experimentation. Luckily for science, but unluckily for individuals, medicine offers many “natural experiments.” But in the area of population genetics and history analyses of pedigrees or family based studies centered around particular traits and genes have limitations of…

Obesity & ancestry in African Americans

Another study on obesity & Africans, with a slight twist, Admixture Mapping of Obesity-related Traits in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study: Obesity is an important cause of morbidity and mortality worldwide. In the United States, the prevalence of obesity is higher in African Americans than whites, even after adjustment for socioeconomic…