Inbreeding

Gene Expression

Tag archives for Inbreeding

Inbred dogs & GWA

Could be the title of the paper. Anyway, Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex: …Incidences of specific diseases are elevated in different breeds, indicating that a few genetic risk factors might have accumulated through drift or selective breeding. In this study, a GWA study with 81 affected dogs (cases)…

The Hapsburgs are one of those royal families who are relatively well known, and in the minds of the public are to a great extent the emblems of the downsides of inbreeding. To painting to the left is of Charles II, king of Spain, the last of the Spanish Hapsburgs, and an imbecile whose premature…

Decline in inbreeding over time

Genetic Future points to a new paper which suggests that inbreeding is declining over time. Their methodology involved surveying different age cohorts and noting the decreased levels of homozygosity among the youth. Dienekes points out that the use of living people might simply be confounding inferred mating patterns with the fact that homozygous individuals have…

If you read an older work like The History and Geography of Human Genes based on classical genetic markers Sardinia stands out on charts of genetic distance. This is probably due to the fact that Sardinia is an island and gene flow from surrounding regions is relatively limited due to the physical barriers. So the…