Vitamin D

Gene Expression

Tag archives for Vitamin D

Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren: Design: From December 2008 through March 2009, we conducted a randomized, double-blind, placebo-controlled trial comparing vitamin D3 supplements (1200 IU/d) with placebo in schoolchildren. The primary outcome was the incidence of influenza A, diagnosed with influenza antigen testing with a nasopharyngeal swab…

Vitamin D & T cells

I have mentioned before the current fad in vitamin D related papers in the medical literature. It’s also broken into the pop culture Zeitgeist as well, I regularly get forwards on the topic. Here is a Google Trends chart for the United States: The history of medicine is, unfortunately, rather similar to the history of…

I got interested in vitamin D a few years ago because I was trying to figure out a plausible explanation for why many of the genetic variants implicated in lighter skin seem to have risen in frequency relatively recently, 10,000 years ago, when modern humans have been extant at higher latitudes on the order of…

Low Vitamin D Causes Problems For Acutely Ill Patients: Dr Paul Lee, Professor John Eisman and Associate Professor Jackie Center, researchers at Sydney’s Garvan Institute of Medical Research, examined a cohort of 42 Intensive Care Unit (ICU) patients. Forty-five percent turned out to be Vitamin D deficient. … When the team correlated the Vitamin D…

Swine influenza, seasonality, and the northern hemisphere: This history demonstrates the seasonality of pandemic influenza, and suggesta that spread of A/California/09/2009 in the northern hemisphere is not imminent. Based on this regularity, the epidemic in Mexico should be over no later than the end of May. While it is not ‘impossible to see the current…

Folate & fertility & skin color

On the order of ~1 million years ago humans seem to have evolved dark skin. While light skin evolved several times, it looks like dark skin exhibits an “consensus sequence,” so that all dark skinned peoples seem to have the same genetic architecture. This chart (from Signatures of Positive Selection in Genes Associated with Human…

See FuturePundit & Effect Measure. Also see H5N1. CDC recommends (especially for residents of California & Texas):

Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey: The median serum 25(OH)D level was 29 ng/mL…and 19%…of participants reported a recent URTI [recent respiratory tract infections]. Recent URTI was reported by 24% of participants with 25(OH)D levels less than 10 ng/mL, by 20%…