Biology

Category archives for Biology

I’ve made no secret of my disdain for self-proclaimed “animal rights” activists, the ones who are more than willing to terrorize scientists doing research to understand disease better and thereby develop better treatments and even cures. None of this means that I am some sort of “animal abuser” (to steal the animal rights jargon) or…

Grant time again! Since today–yes, today!–is the deadline for a rather big grant I’m writing (not quite R01 level, but a respectable three year project if I can get it), I was up until the wee hours of the morning trying to put this sucker to bed. Being the ever-benevolent blogger, though, far be it…

Back in December, I took issue with a highly irritating article by someone who normally should know better, Jonah Lehrer, entitled The Truth Wears Off: Is There Something Wrong With the Scientific Method?, so much so that I wrote one of my typical long-winded deconstructions of the article. One thing that irritated me was contained…

During the six years of its existence, one frequent complaint I’ve had on this blog, it’s been about how the press covers various health issues. In particular, it’s depressing to see how often dubious and even outright false health claims, such as the claim that vaccines cause autism, that cell phones or powerlines cause cancer,…

NOTE: Orac was actually out rather late last night. It turns out that the more administrative responsibility he somehow seems to find the more he has to go out to dinner as a part of various cancer center-related functions. As a result, he is recycling a bit of recent material from elsewhere that he in…

Six years in the blogosphere…

Has it really been six years? Six years ago today, on a dim and dreary Saturday in December, almost on a whim I sat down, went to Blogspot, and started up the first version of Respectful Insolence with an introductory post with the cliched title, Please allow me to introduce myself. Here it is, six…

No, no, no, no, no! I hate it when a fellow ScienceBlogger goes astray! Fortunately, it’s been a long time indeed since I felt obligated to administer a dose of Insolence, Respectful or otherwise, to a fellow ScienceBlogger. It’s been even longer (as in, I think, never) that I’ve ever seen one whose resource I…

You may have noticed that there wasn’t the usual 3,000 word heapin’ helpin’ of Insolence this morning. That’s because I happened to be away visiting family in Chicago over the weekend and I just didn’t have time to come up with anything–and I enjoyed myself too thoroughly to worry overmuch about it. In case you’re…

One of the great things about having declared Vaccine Awareness Week is that it gives me a convenient excuse to revisit topics and blog posts that I had meant to address but that somehow didn’t make the cut the first time around. This is the sort of thing that happens fairly frequently in blogging, where…

The Lorne Trottier Symposium is over, and it went quite well. Amazingly, even though I had to follow Michael Shermer’s talk, people told me I didn’t suck, which made me feel better. Oh, there was this issue of a guy who wanted to tout Royal Rife and his machine. He wouldn’t have irritated me so…

Every so often, real life intrudes on blogging, preventing the creation of fresh Insolence, at least Insolence of the quality that you’ve come to expect. This is one of those times, thanks to R01 deadlines. So enjoy this bit of Classic Insolence from back in September 2007 that, shockingly, as far as I can tell…

Here and elsewhere in the blogosphere, over the last several years, what started out as a more general interest in skepticism and science with a natural focus on medicine and a side interest in combatting Holocaust denial became more focused on promoting science-based medicine. As the saying goes, “Science, it works, bitches,” and I make…

Over the years, I’ve written a lot about cell phones and the scientifically highly implausible claim that radio waves from cellular telephones can lead to brain cancer and other health problems. For example, two years ago, when the then director of the respected University of Pittsburgh Cancer Center, Dr. Ronald B. Herberman issued a warning…

If there’s one aspect of medical education that I consider to be paramount, at least when it comes to understanding how to analyze and apply all the evidence, both basic science and clinical, it’s a firm grounding in the scientific method. I advocate science-based medicine (SBM), which is what evidence-based medicine (EBM) should be. SBM…

Fructose and pancreatic cancer

I hate science press releases. Well, not exactly. I hate science press releases that hype a study beyond its importance. I hate it even more when the investigators who published the study make statements not justified by the study and use the study as a jumping off point to speculate wildly. True, it’s not always…

I’ve been a critic of Arianna Huffington’s massive group blog, The Huffington Post, since three weeks after it first blighted the blogosphere. That’s when I first noticed that the “health” section (such as it is) of HuffPo had already become a wretched hive of scum and anti-vaccine quackery, something I began documenting again and again…

Grant writing status report

Status report: I’m in the home stretch of writing my grant. It will be finished by 8 AM, when I have to be at work again, in tip top mental condition for the meetings I’ll have to endure all morning. (What the heck happened to not doing anything substantive the day before a holiday weekend?…

I don’t know if I need to get out the infamous paper bag or–even worse–the Doctor Doom mask out yet. As you may recall (if you are a long time reader, anyway) is that the mind-numbing stupidity of certain MDs has driven me to want to hide my face in utter shame at the embarrassment…

I’ve had the immense good fortune to have trained and ultimately become a physician-scientist during a time when the pace of discovery and the paradigm changes in science have occurred just over the course of my career in medicine and science has been staggering. microRNA, the shift from single gene studies to genomics, the development…

Of all the “alternative” therapies out there, arguably the most studied is the modality known as acupuncture. Perhaps the reason is that, unlike homeopathy, which based on physics, chemistry, and biology alone is so implausible that, for it to “work,” huge swaths of well-established physics and chemistry would have to be shown to be not…

Anyone who’s been reading this blog for any length of time longer than a few weeks knows what I think of Deepak Chopra. Indeed, he’s been a recurring topic here since the very beginning (just type his name into the search box for this blog if you don’t believe me). In fact, Chopra has “distinguished”…

If there’s one thing that has irritated me (one might even say, irritated me enough to start this blog), it’s ideology or religion trumping science. Perhaps the most annoying form of this disease is the tendency of the right wing whackosphere to do everything and anything it can to distort and twist science to agree…

Cancer research: Is now our time?

The following is a rather curious promotional video that was shown at the plenary sessions of the AACR 2010 meeting. I first saw it yesterday, and thought my readers might be interested in it while I’m winding my way home: It’s basically a compendium of various facts about cancer and cancer research with a rather…

Last month, in response to some truly despicable activities by animal rights zealots, I wrote a series of posts about how animal rights activists target even researchers’ children and appear to fetishize violence. This simply continued a string of posts that I’ve done over the years, the longest (and, in my not-so-humble-opinion, the best) deconstructs…

Feeling stressed? Run down? Is your face not as chipper and toned as it might be? Of course you are. We all are from time to time, particularly as we journey into middle age and beyond. So what better than a bit of pampering at the spa? There’s nothing like a soothing facial to get…