cancer
cmonforton | October 20, 2017The headlines are grabbing people's attention:
CBC News: "Pollution causing more deaths worldwide than war or smoking"; CNN: "Pollution linked to 9 million deaths worldwide in 2015, study says"; BBC: "Pollution linked to one in six deaths"; Associated Press: "Pollution killing more people every year than wars, disaster and hunger, study says"; The Independent: "Pollution is killing millions of people a year and the world is reaching 'crisis point', experts warn."
News outlets are referring to a report released yesterday by The Lancet Commission on Pollution and Health. The report’s authors…
oracknows | October 8, 2017Over the last two Mondays, I've been writing about an unproven cancer therapy that I hadn't really heard much about before. The cancer treatment is called Rigvir; it is manufactured in Latvia and marketed primarily through a Latvian entity called the International Virotherapy Center (IVC).
To recap, Rigvir is an unmodified Echovirus, specifically ECHO-7, that, according to the IVC, seeks out cancer cells, replicates in them, and thus lyses the cancer cells (causes their membranes to break, spilling out the cancer cells contents, thus killing the cell), hence the term "oncolytic virus."…
oracknows | October 3, 2017It's October again, which is Breast Cancer Awareness Month. As someone who takes care of breast cancer patients, I have a love-hate relationship with October. On the good side, I like seeing positive messages about what's going on in breast cancer research, advocacy, and clinical treatment. On the other hand, the quacks come out. I also see a lot of bad breast cancer studies. You might think that I'd like that too because it provides blog fodder. I could actually do without that, but in this case I happened to come across a "study" that illustrates why I detest how those promoting unproven…
oracknows | October 1, 2017Last week, I wrote about Rigvir, a highly dubious cancer therapy developed in Latvia. Rigvir is an oncolytic virus, and its proponents claim that it targets only cancer cells for destruction, leaving normal tissue alone. Its history and how it came to be approved in Latvia in 2004 and added to the Latvian Health Ministry's list of reimbursable medications in 2011 remain rather mysterious, but how it is being marketed does not. For example, Rigvir has become a new favorite treatment at a number of quack clinics, such as the Hope4Cancer Institute in Mexico, where Rigvir is offered along with…
oracknows | September 24, 2017This blog is based in the United States, and I'm an American. Unfortunately, this produces a difficult-to-avoid baked-in bias towards medicine as it is practiced in the US and, to a lesser extent, as it is practiced in the English-speaking world, because English is my language and I can read accounts coming out of English-speaking countries. The same bias exists with respect to pseudo-medicine, with our concentration having been primarily on either quackery that is practiced in the US, UK, Canada, or Australia (and sometimes New Zealand). It's not because I'm not interested in medicine and…
oracknows | September 17, 2017For nearly as long as I can remember, I've been a fan of Jeopardy! Indeed, if I'm at home at 7:30 PM on a weeknight, Jeopardy! will usually be on the television. Given that, I remember what was basically a bit of stunt programming in 2011, when Jeopardy! producers had IBM's artificial intelligence supercomputer Watson face off against two of the most winning champions in the history of the show, Ken Jennings and Brad Rutter. Watson won, leading Jenning's to add to his Final Jeopardy answer, "I, for one, welcome our new computer overlords."
Watson's next challenge was similarly highly hyped:…
oracknows | September 7, 2017Regular readers know that, as a cancer surgeon, I become particularly worked up about stories of naturopaths taking care of cancer patients, which all too often end in disaster for the patient. I've lost count of how many naturopaths I've seen, either on their websites, in talks, or in published literature, claiming that they can cure cancer "naturally," using any of a number of unproven methods, an example being the Gerson protocol, a form of quackery involving 13 larges glasses of raw vegetable and fruit juice, around 150 supplements, and five coffee enemas a day, each and every day. Others…
oracknows | September 4, 2017I write frequently about naturopathy here because, of all the dubious pseudoscientific medical "disciplines" out there, naturopathy (along with chiropractic) has achieved the most "respectability." Indeed, as I like to point out in my own specialty (breast cancer), the Society for Integrative Oncology (SIO) even admits naturopaths as members. Indeed, the immediate past president of SIO is a naturopath (and, depressingly, faculty at my medical alma mater, the University of Michigan), as was the SIO president in 2014. So entrenched are naturopaths in SIO that they have been prominent co-authors…
oracknows | August 20, 2017Alternative medicine, by definition, consists of medicine that either has not been shown to work or has been shown not to work. To paraphrase an old adage yet again, medicine that has been shown to work with an acceptable risk-benefit ceases to be "alternative" and becomes simply "medicine."
Unlike the case for many conditions commonly treated with alternative medicine, whether or not a treatment works against cancer is determined by its impact on the hardest of "hard" endpoints: Survival. A patient either survives his cancer or he does not. Even the "softer" endpoints used to assess the…
oracknows | August 6, 2017One of the gratifying things about having been blogging so long—nearly 13 years now!—is that you start to see stories that you wrote about a long time ago resurface, allowing you to see the resolution. For instance, I've not infrequently written about people who, mistakenly believing the blandishments of alternative medicine practitioners that they could forego all that nasty chemotherapy and radiation and survive their cancer to live a happy, normal life, made the disastrous decision to eschew conventional medical therapy and pursue alternative medicine. My interest in this topic comes from…
oracknows | August 3, 2017The moment I have feared ever since Republicans took control of all three branches of Congress last fall has come one step closer to reality. Actually, it's merely one of many. occurrences that I have feared, given that Donald Trump has been our President for over six months. Although you won't find much in the news about it, yesterday the Senate easily passed a federal version of so-called "right-to-try." Senator Ron Johnson, who threatened to hold up Senate business unless a right-to-try rider was approved for the bill funding the FDA for the next seven years, was ecstatic:
I’m proud the…
oracknows | August 2, 2017I wasn't sure if I should do this post, mainly because I could find so little information to elaborate on a bit of information that I discovered. Then I thought about it a bit more. Perhaps my not being able to find out will illustrate my point better than a detailed progress report on a woman whom I blogged about once nearly 16 months ago. Also, it's a hopeful story. At least I think it is, because it looks as though the young woman at the center of it has abandoned quackery.
Basically, this was the story of a young woman with a bad cancer who had eschewed conventional therapy, particularly…
oracknows | July 31, 2017Everything old is new again, or so it always seems with alternative medicine.
Before I explain what I'm talking about a bit more, let me just preface my remarks with an explanation for why there was no post tomorrow. I realize that most people probably don't care that much if I miss a day or two, but I care. Basically, I was in Chicago from Thursday through Sunday taking a rather grueling review course in general surgery offered by the American College of Surgeons. The reason is that I have to take my board recertification examination in general surgery in December. It was an amazing course,…
oracknows | July 23, 2017Over the last two or three weeks, you might have noticed a disturbance in the alternative medicine force. Unlike disturbances in the Force in Star Wars movies (which usually result from horrors like the obliteration of millions of lives on Alderaan), this was a joyous, celebratory disturbance in the mystical nonexistent energy fields in which promoters of alternative medicine cancer cures and haters of chemotherapy and "conventional" cancer treatment (the two almost always go together) thought that a major study in a reputable journal had put yet another "final nail in the coffin of…
oracknows | July 17, 2017There's a good rule of thumb about headlines (other than Betteridge's Law of Headlines) that I use when perusing articles. It's particularly useful for evaluating headlines about medical and science stories. Basically, if a headline says something like, "everything you know about X is/might be/could be wrong" or "everything scientists know about X is/might be/could be wrong," it's a highly reliable indication that much of what is in the article that follows is very likely to be unmitigated, grade-A bullshit. I realize that it might be confirmation bias on my part (I am, after all, a skeptic…
oracknows | July 17, 2017Here we go again.
It's been a while since I've written about the cruel sham that is known as "right to try." Anyone who's been reading this blog a while (or even read the first sentence of this paragraph) knows that I'm not a fan of right-to-try laws. Basically such laws, which have sprung up like kudzu since the movement to pass them gained momentum three years ago, claim to allow terminally ill patients the “right to try” experimental therapeutics. Thus far, they have been sold to the public as giving terminally ill patients “one last shot” and touting how such laws could save some of their…
cmonforton | June 13, 2017[This post is dedicated to Doug Larkin. Doug was the co-founder of the Asbestos Disease Awareness Organization. He suffered in recent years with Amyotrophic Lateral Sclerosis (ALS) and passed away yesterday.]
Dallas-based OxyChem imports about 300,000 pounds of asbestos each year. Yes, asbestos. The deadly mineral that most Americans think is banned (it's not) and responsible for about 15,000 U.S. cancer deaths annually.
OxyChem is likely the largest asbestos importer in the U.S. The company is required under the Toxic Substances Control Act (TSCA) to report its asbestos imports to the EPA.…
oracknows | June 4, 2017This is the sort of story that I really hate but feel obligated to discuss. I hate these stories because they usually portend the unnecessary death of a cancer patient, often a child with cancer whose parents refuse chemotherapy or who refuses chemotherapy and is unfortunate enough to have a parent who either has alternative medicine proclivities herself, lacks the guts to tell the child that he's getting treated for his own good and he doesn't have a choice in the matter, or, in a couple of cases that I've discussed, conflates using indigenous people's medicine instead of chemotherapy as a…
kkrisberg | May 16, 2017At BuzzFeed, Kate Moore tells the story of the “radium girls,” the hundreds of women during WWI who worked painting watch dials with luminous radium paint — a substance that would eventually poison and kill them even though they were told it was perfectly safe. What followed was years of employers covering up and denying evidence that radium was killing workers, while berating the women for attempting to get help with their mounting medical bills.
Eventually, Moore writes, their fight for justice led to one of the first cases in which an employer was held responsible for the health of workers…
oracknows | May 4, 2017I'm having flashbacks now. I feel as though it's 2012, and I was just in the midst of examining the Houston cancer quack known as Dr. Stanislaw Burzynski. As you recall, he's the Polish expat doctor who discovered peptides in the blood that he dubbed "antineoplastons" and postulated to be endogenous cancer suppressors. He ultimately made them into a cancer treatment that he's been using on patients for over 40 years now, despite never having demonstrated its efficacy or safety. Despite that, he's become a rock star in the world of alternative cancer cures, with two propaganda movies disguised…