Clinical trials

Category archives for Clinical trials

The overarching goal that proponents of so-called “complementary and alternative medicine” (CAM) or, as is becoming the preferred term, “integrative” medicine is the mainstreaming of the “unconventional” treatments that fall under the rubric of these two terms. Indeed, that’s the very reason why they so insisted on the shift from calling it CAM to calling…

My opinion about medical marijuana has been fairly consistent. First, the claims made by its advocates for it far exceed the evidence for its benefit, which is why I’ve referred to it as the “new herbalism.” Of course, it’s not really very new, but it is herbalism in that medical marijuana advocates make grandiose claims…

When I wrote yesterday about the cruel sham that is “right-to-try,” , one criticism (among many) that I made of these misguided, profoundly patient-unfriendly laws was that I have as yet been unable to find a single example of a patient who has managed to obtain access to an experimental therapeutic through such a law,…

Last year, I did several posts on what I consider to be a profoundly misguided and potentially harmful type of law known as “right-to-try.” Beginning about a year and a half ago, promoted by the libertarian think tank known as the Goldwater Institute, right-to-try laws began popping up in state legislatures. I wrote about how…

Dedicated to lilady. One of the disadvantages of writing for this blog is that sometimes I feel as though I spend so much time deconstructing bad science and pseudoscience in medicine that I’m rarely left with the time or the opportunity to discuss some interesting science. Of course, even when I do that, usually it’s…

So busy was I writing about America’s quack Dr. Mehmet Oz and, of course, the FDA hearing on regulating homeopathy that I didn’t take note of a story that came out the other day examining a study looking at the association between MMR vaccination and autism. More correctly, the study examines the lack of association…

Dr. David Katz is undoubtedly a heavy hitter in the brave new world of “integrative medicine,” a specialty that seeks to “integrate” pseudoscience with science, nonsense, with sense, and quackery with real medicine. In fairness, that’s not the way physicians like Dr. Katz see it. Rather, they see it as “integrating” the “best of both…

Why, oh why, did I look at GreenMedInfo again? You remember GreenMedInfo? It’s yet another wretched hive of scum and quackery, but with a twist. Its proprietor, Sayer Ji, thinks he’s an expert at interpreting the biomedical literature. Unfortunately, as he demonstrates time and time again with depressing regularity, he is nothing of the sort.…

It’s no secret that I don’t have a high opinion of naturopathy. Just enter the word “naturopathy” into the search box of this blog, and you’ll quickly see what I mean. Indeed, when last I mentioned the topic a couple of weeks ago, I was discussing the revelations of Britt Marie Hermes, a former naturopath…

Ancient cancer

As I sat on my couch last night, laptop sitting in front of me, I awaited the Ken Burns adaptation of Siddartha Mukherjee’s excellent book The Emperor of All Maladies into a three part television documentary to air on PBS. I’m not sure whether I’ll blog the show or not, but if I do I’ll…

If there’s one thing that’s become clear to me over the years about acupuncture, it’s that it’s nothing more than a theatrical placebo. Many are the times that I’ve asked: Can we finally just say that acupuncture is nothing more than an elaborate placebo? Most recently, I asked this question in 2012. What science-based medicine…

Yesterday was a very strange day, at least on the Internet. I really should learn to remove Twitter from my iPhone on Wednesdays. Why? Wednesdays tend to be my administrative days. I’m not in clinic seeing patients nor am I in the operating room. That’s why Wednesday tends to be one of the two days…

Now that we’re solidly into 2015, it’s a good time to check in on what the legislative priorities are going to be among various advocates of quackery and “health freedom” (but I repeat myself). There’s a new Republican Congress, and a lot of chairmanships are going to be reshuffled, with various legislators finding themselves in…

So here it is, already a week into 2015. Truth be told, I’m still finding myself having a hard time believing that it’s already 2015, but then I say that about every year in early January. Be that as it may, I’ve already seen one hopeful sign that it could be a decent year when…

Seven years ago I returned to Michigan, where I was born and spent the first quarter century of my life, after an absence of more than 20 years. In the interim, I had done my surgical residency and earned my PhD in Cleveland, a surgical oncology fellowship in Chicago, and worked in New Jersey at…

It should come as a surprise to no one that I’m not exactly a fan of “integrative oncology”—or integrative medicine, or “complementary and alternative medicine” (CAM), or whatever its proponents want to call it these days. After all, I’ve spent nearly ten years writing this blog and nearly seven years running another blog dedicated to…

One thing that happened this week that I didn’t get around to writing about is the 100th anniversary of the birth of Jonas Salk, which was October 28. In the annals of medicine, few people have had as immediate a positive effect as Jonas Salk did when he developed the inactivated polio vaccine (IPV). At…

R.I.P., McKenzie Lowe. Unfortunately, Stanislaw Burzynski was no more able to save you than anyone else, his claims of great success treating pediatric brain tumors notwithstanding: HUDSON — Thirteen-year-old Hudson resident McKenzie Lowe died Friday evening after a 2-year-battle against an aggressive and inoperable brain stem tumor. McKenzie died at 10:27 p.m. in her own…

One of the biggest medical conspiracy theories for a long time has been that there exist out there all sorts of fantastic cures for cancer and other deadly diseases but you can’t have them because (1) “they” don’t want you to know about them (as I like to call it, the Kevin Trudeau approach) and/or…

The antivaccine movement and conspiracy theories go together like beer and Buffalo wings, except that neither are as good as, yes, beer and Buffalo wings. Maybe it’s more like manure and compost. In any case, the antivaccine movement is rife with conspiracy theories. I’ve heard and written about more than I can remember right now,…

Supporters of science-based medicine and keeping pseudoscience out of medicine have a few years to prepare for an onslaught of crappy studies “proving” the value of “integrative” oncology. No doubt at this point you’re wondering just what the heck Orac is talking about. I will tell you. It involves an institution we’ve encountered before and…

These things always seem to happen on Friday. Well, not really. It’s probably just confirmation bias, but it seems that a lot of things I’d like to blog about happen on a Friday. That leaves me the choice of either breaking my unofficial rule not to blog on the weekend or waiting until Monday, when…

Do negative clinical trials change practice?

One of the central themes of this blog from the very beginning is that all medicine, regardless of where it comes from or how it was developed, should be held to a single science-based standard with regards to efficacy, effectiveness, and safety. I tend to focus primarily on “complementary and alternative medicine” (CAM), now more…

Ever since the latest outbreak of Ebola viral disease in West Africa, there has been panic that’s metastasized to the US, even though the risk of a major outbreak here is very low. Unfortunately, whenever there’s panic over a disease, whatever the disease is, there soon follows quackery in response to that panic, from quacks…

Of all the quacks and cranks and purveyors of woo whom I’ve encountered over the years, Deepak Chopra is, without a doubt, one of the most arrogantly obstinate, if not the most arrogantly obstinate. Sure, a quack like Mike Adams wins on sheer obnoxiousness and for the sheer breadth of crankery to which he ascribes,…