Clinical trials

Respectful Insolence

Category archives for Clinical trials

The central mystery of Stanislaw Burzynski is how he keeps managing, no matter what is thrown at him by state and federal medical authorities, to keep on treating patients with deadly cancers. He’s like the Energizer Bunny; he just keeps going and going and going and going. Or maybe he’s like the game Whac-A-Mole™, where,…

Three weeks ago, USA TODAY published an expose of the Burzynski Clinic by Liz Szabo that was devastating in its scope and detail. Early on, Stanislaw Burzynski and his minions tried to do some damage control, with hilarious results given how inept and unconvincing his excuses were for all the violations of ethics and patient…

I’m not really happy to have to write this post, but a blogger’s got to do what a blogger’s got to do. The reason is that Katie Couric has done something requires—nay, demands—a heapin’ helpin’ of Orac’s characteristic Respectful Insolence. Why should I give the proverbial rodent’s posterior about who gets the Insolence today? The…

A man on TV is selling me a miracle cure that will keep me young forever. It’s called Androgel…for treating something called Low T, a pharmaceutical company–recognized condition affecting millions of men with low testosterone, previously known as getting older. —The Colbert Report, December 2012 And now for something completely different…sort of. Thanksgiving is tomorrow,…

I know I have readers who are neuroscientists. However, do I have readers who are currently attending the 4th Quadrennial Meeting of the Society of Neuro-Oncology in San Francisco going on this weekend? Why do I ask? Given the Regular readers might suspect that it has to do something with a man who has become…

I was very pleased last Friday, very pleased indeed. Given the normal subject matter of this blog, in which we face a seemingly unrelenting infiltration of pseudoscience and quackery into even the most hallowed halls of academic medicine, against which we seem to be fighting a mostly losing battle, having an opportunity to see such…

I’ve made no secret of how much I despise Stanislaw Burzynski, the self-proclaimed cancer doctor and medical researcher who has been treating patients with an unproven, unapproved chemotherapeutic agent since 1977, seemingly slithering around, under, over, and past all attempts to investigate him and shut him down. Along the way, Burzynski has become a hero…

It’s been a while since I’ve written about Stanislaw Burzynski, the Houston cancer doctor who inexplicably has been permitted to continue to administer an unproven cancer treatment to children with deadly brain cancers for nearly 37 years now. Beginning in 1977, when he left Baylor College of Medicine and opened up the Burzynski Clinic, Burzynski…

Why we fight for patients

Never let it be said that Orac can’t match Mark Crislip in shameless promotion. The world might indeed need more Mark Crislip™, but I like to think that it needs a bit more of his friends, too. So, in that spirit, here are the videos, recently released by the James Randi Educational Foundation, of Bob…

If there’s one medical treatment that proponents of “alternative medicine” love to hate, it’s chemotherapy. Rants against “poisoning” are a regular staple on “alternative health” websites, usually coupled with insinuations or outright accusations that the only reason oncologists administer chemotherapy is because of the “cancer industrial complex” in which big pharma profits massively from selling…

As I mentioned yesterday, one of the things I do on this blog that I consider to be a public service is to analyze cancer cure testimonials that are used to sell alternative medicine. Indeed, I did just that yesterday for a testimonial by someone Chris Wark, who will probably feature again one more time…

Here we go with another one. Three weeks ago, I mentioned in a post that the week of October 7 to 14 was declared by our very own United States Senate to be Naturopathic Medicine Week, which I declared unilaterally through my power as managing editor of Science-Based Medicine (for what that’s worth) to be…

Cancer chemotherapy and obesity

In medicine, particularly oncology, it’s often the little things that matter. Sometimes, however, the “little things” aren’t actually little; they just seem that way. I was reminded of this by a story that was circulating a couple of weeks ago in the national media, often under titles like “Obese cancer patients often shorted on chemo…

Tomorrow, as mandated by the Patient Protection and the Affordable Care Act (PPACA, often called just the Affordable Care Act, or ACA, or “Obamacare”), the government-maintained health insurance exchanges will open for business (that is, assuming the likely government shutdown doesn’t stop them temporarily). This post will be basically a followup to a post I…

I’ve written a lot about Stanislaw Burzynski and what I consider to be his unethical use and abuse of institutional review boards and clinical trials. Before that, I used to regularly write about Mark and David Geier and their unethical use and abuse of IRBs and clinical trials. In both cases, I lamented how they…

About a week and a half ago, I wrote about a local oncologist who was arrested by the FBI for massive Medicare fraud in which physician involved diagnosed cancers that weren’t there, gave chemotherapy to patients who either didn’t have cancer or were in remission and thus didn’t need it, and had developed a self-referral…

Recently, I got an e-mail from someone who had just discovered my blog that made me think a bit, which is usually a good thing. At least, in this case it was. Basically, this reader asked me a question I hadn’t been asked in a very long time and hadn’t thought about in a very…

“Alternative medicine,” so-called “complementary and alternative medicine” (CAM), or, as it’s become fashionable to call it, “integrative medicine” is a set of medical practices that are far more based on belief than science. As my good bud and collaborator Mark Crislip so pointedly reminded us last week, CAM is far more akin to religion than…

Time really does fly. It’s hard to believe that it’s been over a week since I gave my big (to me, at least) talk at TAM. It’s equally hard to believe that it’s been more than a week since I had the honor of being kicked out of Penn Jillette’s Private Rock & Roll Bacon…

Believe it or not, I’m going to do Eric Merola (who doesn’t particularly like me, to the point of thinking, apparently, that I’m a white supremacist who doesn’t like evidence but does like to eat puppies) a favor. Having been away at TAM, somehow I missed this. Well, actually, I didn’t miss it, but somehow…

As I write this, I’m winging my way home from TAM, crammed uncomfortably—very uncomfortably—in a window seat in steerage—I mean, coach). I had thought of simply recounting the adventures of the contingent of skeptics with whom I’m associated who did make it out to TAM to give talks at workshops and the main stage and…

Here we go again. Oh, well. These things come in waves, and sometimes I have theme weeks. Right now, this week appears to be developing into a week of quackademic medicine involving dubious acupuncture studies. Yesterday, it was acupuncture for lymphedema after breast cancer surgery, a study coming right about what is rapidly becoming the…

I want my ANP! [NOTE ADDENDUM]

[NOTE ADDENDUM.] It’s been a (mostly) all Stanislaw Burzynski week. I had been thinking of finishing up with a post about something completely unrelated; that is, until people started sending me a link. Also, because I was out last night with my wife in celebration of our wedding anniversary, I didn’t have time for anything…

It was a busy day yesterday, and I had less time than usual to attend to the blog, but that’s OK. This random thought popped into my head after spending the last three days writing about Stanislaw Burzynski, first reviewing Eric Merola’s hagiography and infomercial about him, then seeing how well the BBC did in…

I realize that I’ve been focusing on Stanislaw Burzynski the last couple of days, but it’s just been one of those weeks. Between the release of Eric Merola’s latest paean to the Brave Maverick Doctor and BBC Panorama’s report on Burzynski and his activities, it’s been an eventful week. My review of the second Burzynski…