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All of the candidates being considered by President Trump for FDA Commissioner believe that the FDA is too strict in its standards for approving new drugs. In a commentary in Nature last week, two bioethicists argued that, at least in terms of preclinical data, the standard of evidence is actually too low. Which is correct?

The latest study being promoted as evidence that vaccines cause autism is truly atrocious. Basically, like many epidemiological studies examining putative links between vaccines and adverse health outcomes, it’s mistaking statistical noise for signal. What’s odd about this study is that not a single statistician or epidemiologist appears to have been involved with its design or execution, although a lawyer, a health economist, and an investment banker were.

Last night was a bit weird. I think too many days of only getting a few hours of sleep finally caught up to me, and I crashed by around 9:30 PM. So, contrary to usually happens, when I say this post will be briefer than usual, I actually mean it; I have even less time…

They’re here, they’re there, they’re everywhere! If you believe certain quacks, nanoparticles are the new One True Cause of All Disease, and the evil food industry and big pharma are trying to poison you with them.

You don’t tug on Superman’s cape, people.

“You need to detox.” How many times have you heard or read this? Maybe a friend of yours suggested it for the New Year. Maybe you saw it on a website, in a magazine, or as part of an ad. I like to say sometimes, “Toujours les toxines,” because in many branches of alternative medicine…

When it comes to vaccines, sometimes skeptics think that all is lost, that the antivaccine movement has won. A new Pew Research survey suggests reasons for hope.

It is an article of faith among antivaxers that vaccines are “dirty” and “contaminated.” So when antivaccine “scientists” try to show how contaminated vaccines are and wind up actually showing how pure they are, I laugh.

I must admit that the last couple of weeks have been rather grim here on the old blog. Betweemn Donald Trump’s White House spewing , an unfortunate patient embracing quackery, pseudoscience at the VA, and more. So it is that I feel as though it might not be a bad idea to step back for…

I always wondered how low Donald Trump could go. Now I know. Only I fear this is nowhere near the bottom.

About a week ago, I happened upon a number of stories about a study and project that demonstrates a key difference between science and pseudoscience. They had titles like, “Rigorous replication effort succeeds for just two of five cancer papers” (Science), “Cancer reproducibility project releases first results: An open-science effort to replicate dozens of cancer-biology…

A reader recounts his tale of being referred for fake medicine at a VA facility. Unfortunately, the VA seems to be papering over its lack of resources in the same way that Chairman Mao did in the 1950s, by “integrating” fake medicine with real medicine.

Kellyanne Conaway inadvertently gave us one of the most descriptive terms ever: Alternative facts. Alternative medicine is a lot like alternative facts in that it is unmoored from reality. Like alternative facts, it can also kill.

One of the core beliefs of the antivaccine movement is that there is an “autism epidemic.” The observation that autism prevalence has been climbing for the last two to three decades led some parents with autistic children to look for a cause, specifically an environmental cause, for autism. Because several vaccines are given in the…

Fake news has become an enormous problem. Here, Orac takes a look at a rather fascinating tidbit of fake news aimed at the antivaccine movement. Did the FBI really raid the CDC with the “CDC whistleblower” showing them what to find? Of course not. But a story like this is nearly irresistible to true believers that vaccines cause autism.

Everything old is new again in China. Just as Chairman Mao promoted the “integration” of traditional Chinese medicine with “Western” medicine 65 years ago, the Chinese government today is doing the same thing for the same reasons.

In a (very) few short hours, Donald Trump will take the oath of office and become the 45th President of the United States. I realize that I don’t normally blog about politics, at least other than that related to medicine, but I make no bones about it. I’m dreading 12 Noon ET on January 20,…

So I was distracted yesterday from what I had intended to write about by an irresistible target provided me courtesy of Toby Cosgrove, MD, CEO of The Cleveland Clinic, who bemoaned all those nasty pro-science advocates who had had the temerity to link the antivaccine rant by the director of the Clinic’s Wellness Institute to…

I’ve been pretty hard on The Cleveland Clinic over the years, but justifiably so. After all, The Cleveland Clinic is one of the leading centers of quackademic medicine in the US; i.e., an academic medical center that studies and uses quackery as though it were legitimate medicine. Of course, this is a problem that is…

I’ve written quite a bit about how our soon-to-be President Donald Trump has consistently expressed antivaccine views over the years, such as his oft-stated (on Twitter and elsewhere) beliefs that it’s a “monster” shot that causes autism and infants get “too many” vaccines “too soon.” I’ve heard Trump supporters who are pro-vaccine pooh-pooh these statements…

One of the most important, if not the most important, officials in the federal government responsible for applying science-based medicine to the regulation of medicine is the FDA Commissioner. As you might imagine, particularly after his having met with antivaccinationists like Andrew Wakefield and Robert F. Kennedy, Jr., I am concerned, and I think I…

This week hasn’t been a particularly good week for science. It started out on Monday with news of the social media storm from over the weekend over a blatantly antivaccine screed published the Friday before by the director of The Cleveland Clinic Wellness Clinic. Then, towards the middle of the week, we learned that our…

I was busy last night doing something other than actually blogging. Perhaps I was recovering from the one-two punch of the antivaccine rant penned by the director of the Cleveland Clinic Wellness Institute followed by Donald Trump’s meeting with antivaccine crank Robert F. Kennedy, Jr. Whatever the case I crashed early. However, I can’t help…

I remember when I first heard on Twitter yesterday afternoon that our President-Elect, Donald Trump, was going to meet with longtime antivaccine crank Robert F. Kennedy, Jr. Remembering how Trump had met with antivaccine “hero” Andrew Wakefield before the election and how after the election antivaccine activists were practically salivating over the thought of what…

The fallout from the social media firestorm from the antivaccine rant written by the Medical Director of the Cleveland Clinic Wellness Institute and published by Cleveland.com last Friday has abated but far from faded away. The offending physician, Dr. Daniel Neides, was forced to issue an apology, which was one of the least convincing apologies…