Life Lines

Tag archives for liver

Only mammals express RAGE

RAGE stands for “receptor for advanced glycation end-products”, also known as “AGER”, and new research shows that it first appeared in mammals (Sessa et al., 2014). Despite the name, the receptor also binds other signaling molecules such as HMGB1, S100 proteins, beta-amyloid, phosphatidylserine, among others (Xie et al., 2013). RAGE is reportedly involved in diabetes,…

Fluorescent sushi?

Dr. Miyawaki from the RIKEN Brain Science Institute in Wako, Japan and colleagues have identified the first example of a muscle protein in Japanese freshwater eels (Anguilla japonica) that fluoresces under special circumstances that may lead to improved medical testing (photo above).  The researchers have isolated the protein they named UnaG (after “unagi”, the term…