The Loom

As I’ve mentioned before, my brother Ben also blogs. An editor at Oxford American Dictionaries, he writes about words over at “From A to Zimmer.” Not surprisingly, our blogs usually don’t overlap. But Ben’s latest entry–on very, very long words, has prompted me to pose a question of my own here.

In his post, “Hippopotomonstrosesquipedalianism!”, Ben points out that a lot of the longest words are, as he puts it, “stunt words.” They’re cobbled together from prefixes and suffixes, but never actually used in real life. Hippopotomonstrosesquipedalianism is a case in point–a word that is used to describe long words.

Then Ben moves onto my turf, pointing out that scientists do a wonderful job of manufacturing huge words. The biochemists are arguably the best at it, concocting words like dichlorodiphenyltrichloroethane. But in real life, they just use short-hand: dichlorodiphenyltrichloroethane becomes the easy-to-spell, easy-to-pronounce DDT.

While that may or may not be true for biochemists, it’s not for paleontologists and taxonomists and other scientists who study groups of species. If scientists want to talk about aspidosiphoniforms (a group of wormy species), for example, they don’t just call the critters A-bombs. They learn how to pronounce aspidosiphoniforms without a moment’s hesitation and wait patiently for science writers like me to struggle through the word during interviews.

This raises a question for me–one that scientists may be able to help me with in the comment thread here: what’s the longest word you would actually use in conversation? (One rule of the game: a species name like Tyrannosaurus rex is not a word–but tyrannosaurid is.) Does methylenedioxymethamphetamine just roll of your tongue? Or are these long words just a strict formality, and acronyms the essential tools of the trade? Let’s see who wins this contest.

Update: In the lead as of 1 pm: Immunohistochemistry. 20 letters. Come on, people!

1:10 pm: Hyperphosphorylation. Tied for the lead, with 20. Have we hit a cognitive ceiling here? Can anyone break through?

Friday, 8/24/07 The ceiling is broken: MikeG actually did say ribulosebisphosphatecarboxylaseoxygenase. 47 letters.


  1. #1 Blake Stacey
    August 23, 2007

    I suspect the organic chemists will win this one: they’ve got that verbal heritage from the nineteenth century, when their profession was essentially monopolized by the Germans. Modern IUPAC nomenclature retains the Germanic habit of building long words out of small segments with little in the way of spacing to leaven them, and even dashes only enter the picture because numbers get involved: 2,5-dimethoxy-4-bromophenethylamine, indeed. Physics people like me find “supersymmetry” a mouthful and crunch it down to “SUSY”.

  2. #2 Carl Zimmer
    August 23, 2007

    Blake–The chemists may win on paper, but what about on the tongue?

  3. #3 factician
    August 23, 2007


  4. #4 Jeffrey Fredrick
    August 23, 2007


  5. #5 caspar
    August 23, 2007

    The more time passes the more I lament the fact that the field of psychoneuroendocrinoimmunology never really took off.

  6. #6 Joe McFaul
    August 23, 2007

    I’m a lawyer,not a scientist, but I handled a series of cases involving misdiagnosis of San Joaquin Valley fever.

    After a while, “coccididiomycosis,” “blastomycosis,” and “histoplasmosis” all easily rolled off our tongues, much to the dismay of court reporters.

    I’m sure coccididiomycosis would easily be beaten by scientists who get to practice on long words every day.

  7. #7 Cryptic Ned
    August 23, 2007


  8. #8 Jake
    August 23, 2007

    I’m a grad student in organic chemistry, and I’ll back up Blake’s conjecture. Talking among other organic chemists, there are some things (mostly basic, well-known compounds) that get shortened – hexamethylphosphoramide becomes HMPA, tert-butyldimethylsilyl becomes TBDMS.

    More often, though, you’ve got to use the whole word to assure that what you’re trying to say is understandable, as backwards as it may sound. “OP AChE inhibitors” may be meaningless, but a decent chemist could probably accurately guess what “organophosphate acetylcholinesterase inhibitors” look like and do. Also as Blake pointed out, compound names can get unwieldy fast, but using the standard nomenclature is still better than saying “that one with the six membered ring, three bromines, and an alcohol group.”

    Here’s some you hear often around my lab:


    If ones that include two words count, I’ll throw in

    Supramolecular assembly


    Dipolar cycloadditions

  9. #9 TR Gregory
    August 23, 2007

    I regularly use terms like “pseudogenization” and “rediploidization” and “endopolyploidy”.

  10. #10 Tara C. Smith
    August 23, 2007

    During grad school, the chair of our department studied coccididiomycosis, so yeah, that one’s old hat to me. There are a lot of areas in epidemiology that end up with prefixes that make them ungodly cumbersome. (Technically, I suppose I could call my own area molecuinfectoepidemiology, if people can coin terms like “infectobesity,” right?)

    But for words that already exist, in my own field, how about anthropozoonosis? Not to be confused, of course, with zooanthroponosis…

  11. #11 bug_girl
    August 23, 2007

    I’m afraid the only long word I use semi-regularly is Schadenfreude. (make of that what you will 🙂
    There are short nicknames for most insects with long scientific or proper names.

    And how odd you posted this the same day I was blogging about Hot for words.

  12. #12 Arjun Prasad
    August 23, 2007

    I just quickly searched my Word custom dictionary with perl for the longest word and found coimmunoprecipitation. I don’t do much of it, but other people in the lab do. At 22 letters it’s pretty long.

    Oh, the perl command (if it will be any use to anyone) was:

    perl -ne '$word = $_ if (length $_ > length $word); END {print $word}' Custom\ Dictionary
  13. #13 Ben Zimmer
    August 23, 2007

    Clearly the neuropsychopharmacologists have no problem throwing around 26-letter words. But I guess they better make way for the psychoneuroendocrinoimmunologists.

  14. #14 Blake Stacey
    August 23, 2007

    Now that I think about it, physics and math pack a lot of meaning into people’s names. We’ve got stuff named for Euler and Gauss, and things which Euler or Gauss discovered first but which we named for other people because Euler and Gauss already had so much, and we’ve got lots of hyphenated descriptors. Just yesterday I was proving a theorem with the Laplace-Runge-Lenz vector, for example.

    The winner, in my experience, is the BBGKY hierarchy, a long series of equations which occurs in statistical mechanics. “BBGKY” expands out to Bogoliubov-Born-Green-Kirkwood-Yvon.

    The neuropsychopharmacologists may need long business cards, but they don’t name things after people called Bogoliubov.

  15. #15 MikeG
    August 23, 2007

    Oddly enough… it was ribulosebisphosphatecarboxylaseoxygenase.

    This lovely hexadecameric protein played a major role in my MS thesis.

    It’s not that rare. In fact it is the most common protein in the world. Really.

    (Mostly because it’s terribly inefficient.)

  16. #16 Lara
    August 23, 2007

    Shouldn’t you be looking at the number of syllables rather than the number of letters in the word since you asked for “the longest word [one] would actually use in conversation” rather than in writing?

  17. #17 Carl Zimmer
    August 23, 2007

    MikeG [15] Did you ever actually say “ribulosebisphosphatecarboxylaseoxygenase”? Or just rubisco?

  18. #18 Mo
    August 23, 2007

    On the 1978 album Motor Booty Affair by Parliament, there’s a track called Aqua Boogie (a Psychoalphadiscobetabioaquadoloop).

  19. #19 AD
    August 23, 2007

    As pointed out before, COIMMUNOPRECIPITATION is used commonly in biochemistry and cell biology.

    Not as long but nice mouthfuls:

  20. #20 FreeProton
    August 23, 2007

    If we’re not exclusively into nouns, I’d say one of the most commonly used words in biochemistry papers, “spectrophotometrically” wins so far on a technicality. Then again, we never really speak this much in the lab. I think scientists just don’t like tying their tongues in knots just to get a simple point across. So, rather than asking your undergrad minion to “be so kind as to analyze the sample spectrophotometrically”, you tell them to “spec that crap.” They get it, everyone’s happy.

    As Harrison Ford once said to George Lucas: “George, you can write this sh*t, but you can’t SAY this sh*t.” Amen.

  21. #21 Janne
    August 23, 2007

    I could use my native Swedish, but that’d be cheating I think; we have a completely different tolerance for long words, and some quite complex ideas are routinely expressed as one word. “capital gain tax”, for instance is “realisationsvinstbeskattning” (28 letters, and yes, you’d use it in spoken conversation (if you’re the kind of person to talk about capital gain taxes with people, of course)). Or “Nurse training course” is “sjuksköterskeutbildning” with 22 letters. There’s many others.

    In neurology you have some pretty long anatomical names. But it seems there’s a natural cutoff at around 16-18 letters, or 8 syllables (which seems to be the determinant): “hyperpolarization”, “paleospinothalamic”, “intermediolateral”. Longer than that and people have the sense to cut it up into several words, like “lateral geniculate nucleus”, or shorten it into an abbreviation (for most neurotransmitters, for instance).

  22. #22 jick
    August 23, 2007

    Any computer scientist should be familiar with “nondeterministically” (20 letters). And it’s not too hard to pronounce. 🙂

    Hmm… I must think hard to get past it…

  23. #23 MikeG
    August 24, 2007

    I had to say it a few times, but I added the 1, 5 between the ribulose and the rest of the mess. Which, I guess makes it ribuloseonefivebisphosphatecarboxylaseoxygenase.

    You have to be careful where you leave your phosphates.

    Most of the time, though, it was RuBisCO, or, since I was working with the gene for the large subunit, rbcL.

  24. #24 MikeG
    August 24, 2007

    I forgot the most tongue twisting one that I have had to actually say:

    And people wonder why I got away from studying dinoflagellates…

  25. #25 majasker
    August 24, 2007


  26. #26 the invisible dragon under the bed
    August 24, 2007

    I’m far from being science-literate, but I do try, in my own shabby way. I used to work as a purchasing clerk for a manufacturer of ‘nutritional supplements’ and I was the only person in the building who could pronounce ‘polyenylphosphatidylcholine’; does that count?

  27. #27 andyz
    August 24, 2007

    These words have a strong internal grammar. I’m not sure they qualify as single words in the normal sense. It’s more like Inuit than English.

    I’d like to see a contest for the longest non-agglutinative word. Nondeterministically is pretty good (depending on where you draw that line)

  28. #28 Derek Lowe
    August 24, 2007

    Chemical nomenclature will, as Carl notes, get you into huge words very quickly, although they’re generally broken up with hyphens and the like.

    But here are some of the words that I say in the lab without even thinking about it: nucleophilicity, enantiospecifically, diastereoselectivity (a good solid ten syllables there), exothermically, hydrophobicity, Antimarkovnikov (that one often is written with a hyphen and includes a proper name, so perhaps it shouldn’t count), levorotatory, polyheteronuclear, stoichiometrically, regioselectivity, etc.

    And there are a number of biological terms that I’ve said from time to time, but which don’t come up very often, like mucopolysaccharides or diacylglycerolacyltransferase.

    But when it comes to chemical names, well, even without resorting to hyphens I can think of some that I’ve used more times than I can count: dichlorodicyanoquinone, hexamethyldisilazane, diphenylphosphoranylferrocene, hexamethylphosphoramide, tetramethylethylenediamine, and so on, and on. And while I have said all these at their full length, they’re more commonly referred to as DDQ, HMDS, DPPF, HMPA, and TMEDA, for obvious reasons.

  29. #29 MikeG
    August 24, 2007

    Yeah, I guess the chemicals are cheating.
    In our lab we use the abbreviations anyway: SDS, EDTA, etc.

    The rest is referred to as methyl-ethyl-badsh*t

  30. #30 Patrick
    August 24, 2007

    Beaten already by Mike G, but I have another 20-letter one: “nondeterministically”. (CS majors get big words too!)

  31. #31 Jeffrey A. Kurland
    August 24, 2007

    22 letters & eminently pronoucable: neuropsychopharmacology. Not bad. And a hip field. love&evolution, drBluz

  32. #32 DDeden
    August 24, 2007

    “Humans are merely and obviously aquaterrestuarborealistically adapted from a more primitive (in the scientific sense) basal primate” a naturalist might say, though I don’t recall having heard it…nor have I had the situation to use it to advantage quite yet.

  33. #33 sailor
    August 25, 2007


  34. #34 sailor
    August 25, 2007


  35. #35 Porlock Junior
    August 26, 2007

    Stoichiometrically and nondeterministically are good words, because they’re formed like real words, and they refer to significant things with pretty broad application, and one of them can be figured out by a normal person without specialized training.

    But I’m fond of paradimethylaminobenzaldehyde, with a tale of which I indoctrinated my kids on a longish car ride. The story is from Isaac Asimov, who related that someone during his student days called the compound to his attention, noting that it rolls so trippingly off the tongue that one can sing it. To the tune of the Irish Washerwoman.

    Asimov said it became something of an obsession for a time, and he would unconsciously be humming or muttering it under his breath. On one occasion, he was hanging out in a dentist’s waiting room, and the receptionist commented brightly that it must be fun to be able to sing it in the original Gaelic.

    From there he went on to write of chemical nomenclature, in an article titled “How to Speak Gaelic”. But hum a few bars sometime, and you’ll see how well it fits. For variety, as he also suggested, you could do a bit of “This is the forest primeval, the murmuring pines and the hemlocks…” But does anyone know even that much of Evangeline today?

  36. #36 Jim Hu
    August 26, 2007

    No! Even if you use the long form of RuBisCO, it’s not one word, it’s three:

    Ribulose-1,5-bisphosphate carboxylase/oxygenase

    you don’t get to just merge words as if it’s German, as in Rindfleischetikettierungsüberwachungsaufgabenübertragungsgesetz (63)

  37. #37 Jim Hu
    August 26, 2007

    Those umlauted u’s showed up properly in the preview.. 🙁

  38. #38 Ben Zimmer
    August 26, 2007

    Porlock Junior: John A. Carroll was so inspired by Asimov’s love of “paradimethylaminobenzaldehyde” that he wrote “The Chemist’s Drinking Song” based on the word (to the tune of “The Irish Washerwoman”). Lyrics can be found here.

  39. #39 MikeG
    August 27, 2007

    Thanks, Jim.
    Stealing all my fun… :-p

  40. #40 Jonathan Vos Post
    August 28, 2007

    The scientific name for black lung disease is [i have to insert spaces in this single unbroken word to avoid an error in the form submission system] pneumo ultra microscopic silico volcano conio sis spelt P-N-E-U-M-O-U-L-T-R-A-M-I-C-R-O-S-C-O-P-I-C-S-I-L-I-C-O-V-O-L-C-A-N-O-C-O-N-I-O-S-I-S. caused by the inhalation of coal dust, characterized by formation of nodular fibrotic changes in lungs.”

  41. #41 MattXIV
    August 28, 2007

    I used to say a a good number of longer chemical names out loud frequently, especially when the preferred abbreviation is also commonly used elsewhere. For example, I normally say hexamethylenetetramine since I associate HT with hydroxytryptamines (particularly 5-HT).

  42. #42 Worm_guy
    August 29, 2007

    The longest one I came up with is quite short in this company: haploinsufficiency, but we throw it around the lab a lot.

    Also, practicing scientists often make nouns of verbs and vice versa. For example, we say “homozygose”, not a word, instead of “make homozygous”, which takes longer to say.
    (An example: “Did you manage to homozygose that mutation?”)

  43. #43 Stephen
    August 29, 2007

    When i let slip some really long word, someone nearby will often say “bless you”, because, clearly, i’ve just sneezed. I doubt i’d break any records here. But if my vocabulary is too copious for your diminutive comprehensibility, i will endeavor to elucidate more explicitly. (A classic in 4th grade, anyway.)

  44. #44 factician
    August 29, 2007

    Heh, Worm_Guy, you just made me remember an old joke…

    What does the H. stand for in Jesus H. Christ?



  45. #45 Bill Ware
    September 4, 2007

    Not that long, but trinitrotoluene does have a certain bang to it.

  46. #46 Jerry D. Harris
    September 5, 2007

    Those of us dealing with dinosaurs have had the pleasure in recent years to throw around words like “infrapostzygapophyseal” and “centroprezygapophyseal” (technically not the correct names for the structures they describe, but…). And we vertebrate paleontologists get lovely scientific names, too, like Micropachycephalosaurus, Opisthocoelicaudia, Chometokadmon, Kallikobotion, and Huehuecuetzpalli.

    In a broader realm, evolutionary scientists get frabjuous words like “autapomorphically” and “paleobiogeographically,” which get used on a regular basis.

  47. #47 Niki
    November 8, 2007

    22 letters

  48. #48 cen
    December 31, 2007

    neuropsychopharmacology 23 letters.

  49. #49 Alex Ackerman
    February 29, 2008

    today in school i suggested pneumonoultramicroscopicsilicovolcaniconiousis as a spelling word on our test. (and yes, i can say and spell it off the top of my head.)it has 46 letters and 19 syllables. it is the medical term for lung cancer. i am 13, the bigger the words, the beter. email me at if you have a longer one for me.
    Good luck not getting your tongue tied!

  50. #50 Giggle-wicks
    March 25, 2008

    Antidisestablishmentariansim. 28 letters

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