Microbiome

Mike the Mad Biologist

Category archives for Microbiome

Reporting on the human microbiome–the microorganisms that live on and in us–is quite the rage these days. As someone who is involved in NIH’s Human Microbiome Project, it’s a pretty exciting time because the size and scale of the data we’re able to generate is unprecedented. This also means we have to figure out how…

Since I’m at a Human Microbiome Project meeting, and don’t have time to write, I thought this post from the archives of Mad Biologist was appropriate: A while ago, I talked about some things biologists should learn, and the glaring omission was mathematical fluency. I bring this up because one of the things the Mad…

Yes, you read the title correctly–I’ll get to that in a bit. Nicholas Wade’s article about the Human Genome Project (HGP), “A Decade Later, Genetic Map Yields Few New Cures” has been getting a lot of play. Thankfully, ScienceBlogling Orac summed up perfectly my thoughts about both the science and hype surrounding the HGP, so…

For those who haven’t heard rightwing extremist Virginia Attorney General Ken Cuccinelli has subpoenaed all of the documents related to climatologist Michael Mann’s state-funded research while Mann was at the University of Virginia (italics mine): In papers sent to UVA April 23, Cuccinelli’s office commands the university to produce a sweeping swath of documents relating…

GEBA GEBA Hey!

Since I’m on-route to a Human Microbiome Project meeting (uncharacteristically, it’s being held in a climate-friendly location–Houston; last year, it was held in Boston. In January.), reviewing this paper about the GEBA project, the Genomic Encyclopedia of Bacteria and Archaea, seemed appropriate. Sequencing bacterial genomes not only tells us a lot about the biology of…

It turns your bacteria Jewish*. Seriously, the strong finding of this article was completely ignored. Anyway…. A recent paper describes the effect of circumsion on the bacteria that live on the penis. The authors swabbed uncircumsized and circumsized penises, and then PCR amplified the 16S rRNA gene which is found in all bacteria, and can…

I realize that the typical format for blogging is to find something that pisses you off and then rant about it, but I actually like the recent workshop report by NHGRI, “The Future of DNA Sequencing at the National Human Genome Research Institute.” (pdf file) While I’ll have more to say about the report overall,…

I’m not certain you can have all four. Let’s start at the beginning.