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The author is not a physician. The content on this website does not, and is not intended to constitute medical advice. It should not be relied upon when making medical decisions. It is not intended as a substitute for advice from your physician or other healthcare provider.

June 4, 2009

Slentrol/Dirloapide (Got a fat dog?)

Category: Drugs

Wow. It's not just anticancer drugs for dogs, there are also "lifestyle" drugs. They think they're people!

June 3, 2009

Palladia/Toceranib (Dog cancer drugs)

Category: Drugs

A few months ago, a tyrosine kinase inhibitor anticancer drug for people, this month, one for dogs.

May 11, 2009

Ribosomal Free Love

Category:

Skip to ca. 3 mins for the magic. Using the dance idiom.


May 8, 2009

Dead Horses

Category:

Just as the swine flu story was starting to catch all our attention, 21 horses died. It was like plagues were breaking out everywhere! With a couple weeks' hindsight, people are breathing easier about the pig bug (perhaps prematurely), and we know the horses died of selenium toxicity from a supplement.

April 29, 2009

H1N1/Swine Flu/Antivirals Redux

Category: Drugs

Let's take a visit back to May 2006. The DJIA was above 11,000 and would continue to increase for more than a year. The Da Vinci Code was in theaters. Don Rumsfeld would continue to look very polished in his tab-collar shirts, but his kung fu would serve him for only six more months, when Bob Gates would replace him, following a mid-term election thumpin'. Americans passed the time by applying for VISA cards which literally allowed them to use their homes as credit cards, with which they would buy granite countertops.


But a specter was haunting America - the specter of H5N1, or "bird flu," which threatened to become a pandemic, just as H1N1, or "swine flu" does today. First, we review a link to a bird-flu era series about antivirals and second, a few good links relating to the present situation.


April 22, 2009

NNAL (Cancer pee?)

Category:

There are a number of tobacco-associated compounds that are formed by reactions of nicotine. Cotinine is a metabolite formed from nicotine in the body - it hangs around a relatively long time, so it is a good marker for recent nicotine exposure.

Any undergrads out there into SEM?

Category: Not Really a Molecule

Going through emails, I came across a request from ASPEX to link to a scholarship they're offering. $1,000 and "an opportunity to co-author a poster with ASPEX at Pittcon 2010." If you are an undergrad thinking of applying for this, going to Pittcon might be worth more than the $1,000. You couldn't ask for a better analytical chemistry meeting to attend, and this could be a great place to find a job or grad school advisor.

April 9, 2009

NPPD (Freakin' spy dust!)

Category:

Yesterday, I mentioned naphthoresorcinol as a reagent for aldehyde testing. Did you know: at one point during the Cold War, the Soviets used to put a certain aldehyde on American operatives in the USSR as a tracer?

April 8, 2009

Naphthoresorcinol (Old-timey tests)

Category:

Before the advent of modern spectrometry techniques (NMR and mass spectrometry), there was a compendium of tests to suss out what sort of things were hanging off a molecule. You took your stuff, added a drop of zombie blood, a splash of bat pee, and if black (but not white) soot rose up, you knew you had an arylamine (or at least had some evidence you did). You still see them occasionally in sophomore Organic chemistry labs, but they're going by the wayside, too.

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