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The author is not a physician. The content on this website does not, and is not intended to constitute medical advice. It should not be relied upon when making medical decisions. It is not intended as a substitute for advice from your physician or other healthcare provider.

October 31, 2006

Methyl Iodide (Makin' methyls)

Category: Synthesis

Methyl iodide is another simple organoiodide: Probably the most common lab use is tacking a methyl group onto something; MeI is a great substrate for the SN2 reaction. Despite its ubiquity, methyl iodide isn't nearly the best alkylating agent. It's...

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October 30, 2006

Iodoform (Wet tests and sterile gauze)

Category: Medicine

Another theme week: Iodine. Iodoform is, as the name suggests, the iodine analogue to chloroform. Iodoform, as the Wikipedia entry mentions, isn't the best antiseptic in the world, but they're mistaken in saying it's not used anymore: iodoform impregnated gauze...

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October 27, 2006

L-Methamphetamine (Illegal in the mirror)

Category: Drugs

L-methamphetamine is a fine example of how molecules that vary only in their chirality can have very different biological effects. Chiral molecules have non-superimposable mirror images. L-methamphetamine, at left, below, is found in Vicks Vapor Inhalers. (Notice how they obfuscate...

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October 26, 2006

Kavain (Unlike papain, does not make you strong like Popeye)

Category: Drugs

Kavain is a member of a class of compounds known as the kavalactones. (A lactone is a cyclic ester; click here for examples). Kavain is a species found in the kava plant, which is used by the aboriginal residents of...

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October 25, 2006

Arecoline (Chew on this)

Category: Drugs

Arecoline is a compound that occurs in the seed of the betel palm. It's taken by chewing the nut. Arecoline, like nicotine, binds to certain receptors for acetylcholine. I've grouped them together so you can note the structural similarities. Remember...

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October 24, 2006

Salvinorin A (Houseplant or drug? You be the judge)

Category: Drugs

It's weird drugs for the rest of the week! Salvia probably means one of two things, if anything, to most people: a houseplant (for which purpose it is ubiquitous) or a recreational drug that you can still get your hands...

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October 23, 2006

Back tomorrow.

Category: Not Really a Molecule

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October 20, 2006

InChI (Semantic Web Chatter)

Category: Not Really a Molecule

This might not apply to a lot of the readers, but I think a decent subset might find it important. As you know, it's not so easy to search for chemical information. With most search engines, you're limited to the...

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2-thiopyridine ((Non)-stinky Friday)

Category: Stinky

Pyridines and thiols are two of the stinkiest kinds of compounds you can come across in chemistry. You'd think if you put them together in a molecule, you'd have something nasty. Oddly, you don't: Bafflingly, thiopyridine is apparently odorless. You'll...

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October 19, 2006

Windowpane Redux (Pretty pictures)

Category: Topologically/Geometrically Interesting

For a better idea of how the bond angles look, here is an energy-minimized structure of windowpane (4.4.4.4). Notice how it's (nearly) planar. That central carbon atom (middle gray dot, blues are hydrogens) is the one to watch....

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