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Albendazole (Squirmy little heterocycle)

Category: Dyes
Posted on: January 10, 2007 9:00 AM, by Molecule of the Day

Albendazole is a member of the benzimidazoles - the 6+5 membered ring system at the heart of the molecule. The benzimidazole class of drugs is used to treat many parasitic worm infections. They work by impairing microtubule function.


InChI=1/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)


The benzimidazoles are gratifyingly simple-looking drugs. Contrast Taxol, a much woolier-looking drug that operates on microtubules (in another way, which we'll cover another day; furthermore, that one works on cancer, not worms).

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