5-nitro-2-propoxyaniline is a potent artificial sweetener:
It's banned in the States. Nitroaromatics tend to be tox liabilities. One toxic nitroaromatic with a very specific mechanism of action is 2,4-dinitrophenol.
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5-Nitro-2-propoxy-aniline (Sweet nitroes)
Category: Food
Posted on: August 7, 2007 9:03 PM, by Molecule of the Day
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Comments
Fascinating. Is it supposed that this chemical is capable of shuttling protons across the membrane similar in mechanism to 2,4-dinitrophenol, or is there some other mechanism that we fear? Perhaps it might be reduced to the nitrite and become a carcinogen (on transformation to the nitrosamine? I don't know a lot about nitro metabolism.)
And by the by, I love your blog. Bringing accurate, broad-scope, reader-friendly chemistry to the masses is a noble mission, and one in which I can vicariously take much pleasure! Keep it up!
Brandon
Posted by: The Lilest Naturist | August 8, 2007 12:46 AM
Nothing to say about the molecule today, but I wanted to agree with Brandon's statement - I really appreciate the molecule of the day. Thanks!
Posted by: Size | August 8, 2007 10:56 PM