Now on ScienceBlogs: HeartlandGate: Anti-Science Institute's Insider Reveals Secrets

ScienceBlogs Book Club: Inside the Outbreaks

Profile

Molecules: You'd better learn to live with them.

Search

Recent Posts

Recent Comments

Archives

Blogroll

Other Information


The author is not a physician. The content on this website does not, and is not intended to constitute medical advice. It should not be relied upon when making medical decisions. It is not intended as a substitute for advice from your physician or other healthcare provider.

« Valproate (Do we know anything about drug design?) | Main | Lead (II) Chromate (It's like a toxic party!) »

Triethylene Tetramine (Surprise, a polycation binds DNA)

Category: Drugs
Posted on: January 15, 2008 10:59 PM, by Molecule of the Day

A few months ago, a group published a report that this polyamine was an effective quadruplex ligand, inducing senescence of cancer cells.


It's perhaps unsurprising that this works. I've previously covered Telomestatin (more selective) and TMPyP4 (less selective), but man, just a big charged chain of stuff? Apparently, though, this molecule is used in vivo already, in chelating copper ions in the treatment of Wilson's disease.

Share on Facebook
Share on StumbleUpon
Share on Facebook

TrackBacks

TrackBack URL for this entry: http://scienceblogs.com/mt/pings/61469

Comments

1

fyi, the title and caption are different. I think the title should be 'triethylene ...'

Posted by: azmanam | January 16, 2008 7:35 AM

Post a Comment

(Email is required for authentication purposes only. On some blogs, comments are moderated for spam, so your comment may not appear immediately.)





ScienceBlogs

Search ScienceBlogs:

Go to:

Advertisement
Follow ScienceBlogs on Twitter

© 2006-2011 ScienceBlogs LLC. ScienceBlogs is a registered trademark of ScienceBlogs LLC. All rights reserved.