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The author is not a physician. The content on this website does not, and is not intended to constitute medical advice. It should not be relied upon when making medical decisions. It is not intended as a substitute for advice from your physician or other healthcare provider.

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Biotin (Different things to different people)

Category: Biology
Posted on: February 14, 2008 11:25 PM, by Molecule of the Day

Biotin is just a vitamin to most of us. To a lot of biologists, though, it plays the unlikely role of some of the strongest glue around.


There are proteins known as avidins that bind biotin so strongly that it's pretty much irreversible. If you stick biotin on something you're interested in, and stick avidin on a solid surface, you've pretty much got a molecular glue that's not going anywhere.

Comments

Biotin and the like will also promote the benzoin condensation when the Nanny State whacks your pee-pee for potential hazards. Let's all be too girly to use cyanide like real men.

Will it case-harden steel? I think not.

Posted by: Uncle Al | February 15, 2008 11:25 AM

Actually, it can be used to case harden steel, historicly, collogeneous materials were used as a carbon source through most of the iron age, all you need is carbon rich, not too volatile material to coat the steel. Bone glue was prefered though.

Posted by: Ken Clark | February 15, 2008 3:39 PM

I am always amazed at how ubiquitous biotin is in biochemical studies. I should really look up a crystal structure of biotin-avidin.

Posted by: Vince Noir | February 15, 2008 3:59 PM

Biotin deficiency - a good reason to avoid raw egg white.

Posted by: kirsten | February 16, 2008 8:37 AM

You forgot its most important use: It transfers CO2 molecules in biological systems!

Posted by: Ryan Sullivan | March 6, 2008 4:09 AM

Yes, I agree with Ryan, as biotin plays an important role in the fatty acid biosynthesis of bacteria.

Posted by: Kevin Kuan | March 10, 2008 6:34 PM

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