Silibinin (Liver? I hardly knew her!)

By moleculeoftheday on April 3, 2008.

As Uncle Al mentioned, many antioxidants are ill-tolerated by the liver. However, it loves one antioxidant: silibinin.

Silibinin, found in Blessed Milk Thistle, is actually hepatoprotective - to the extent that it's used in toxic mushroom poisoning in hospitals in Europe!

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Until we get you up to speed with posting the links to ChemSpider I'll do them for you...this one is here:

http://www.chemspider.com/Chemical-Structure.29263.html

Flavonoids overall are cryptoestrogens. Pre-pubescent males who eat lots of soy don't become porn stars (dosed in the womb by Mom liking Hamburger Helper or tofu, etc.). Silibinin is an effective
anti-androgen as therapy for prostate cancer. Cultural flavonoids in food lower the incidence of prostate cancer in a population. There is that small side effect...

http://www.cazv.cz/UserFiles/File/46-17-23.pdf
Estrogenic effects of silymarin in ovariectomized rats
Look at the dose/kg not at the dose/rat, then scale to a 25 kg child.

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