Neurophilosophy

Archives for February, 2008

Neuroscience at Davos

Technology blogger Robert Scoble attended the World Economic Forum at Davos, and made quite a few video recordings of the conversations he had with various people while he was there, which he has uploaded to Qik. In this film, Scoble talks to the Brazilian neuroscientist Miguel Nicolelis, who discussed his recent experiments in which a…

AMPA receptors & synaptic plasticity Part 3

[Introduction|Part 2] It is well established that synaptic strengthening involves the recruitment of AMPARs to the postsynaptic membrane. However, the subunit composition of the receptors has not been investigated closely, so the studies discussed here allow for refinement of this basic model, as they all show that synaptic strengthening involves the incorporation of Ca2+-permeable GluR2-lacking…

John Pezaris emailed me yesterday to say: Last spring, you were kind enough to write an article for your Neurophilosophy blog covering my research into restoring sight to the blind, following the publication of our scientific paper in the Proceedings of the National Academy of Science. Your article was one of the best ones written:…

AMPA receptors & synaptic plasticity Part 2

Following on from the introduction, I now discuss a number of recent studies which demonstrate that synaptic strengthening in different regions of the mammalian brain requires the incorporation of Ca2+-permeable GluR2-lacking AMPA receptors into the postsynaptic membrane of active or newly-potentiated synapses.