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Neurodegeneration:

Optogenetics controls brain signalling and sheds light on Parkinson's therapy

Category: Neuroscience

Optogenetics is a recently developed technique based on a group of light-sensitive proteins called channelrhodopsins, which were isolated recently from various species of micro-organism. Although relatively new, this technique has already proven to be extremely powerful, because channelrhodopsins can be...

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Alzheimer's recapitulates brain development

Category: Developmental Biology

Alzheimer's Disease is the most common form of dementia, affecting more than 400,000 people in the U.K. and some 5.5 million in the U.S. The disease has a characteristic pathology, which often appears first in the hippocampus, and then spreads...

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Aging brains lose their connections

Category: Neurodegeneration

Healthy aging is characterized by a gradual decline in cognitive function. Mental processes such as attention, memory and the ability to process information are at their peak when people are in their 30s and 40s, but as we get older,...

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Cannibalism & the shaking death: A new form of the disease & a possible epidemic

Category: Neurodegeneration

National Library of Medicine / Hot Medical News This silent film clip shows several victims of a disease called kuru. They are - or rather were - members of the South Fore, a tribe of approximately 8,000 people who inhabit...

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Skin cells from an 82-yr.-old ALS patient reprogrammed to form neurons

Category: Neurodegeneration

A team of researchers from Harvard and Columbia University Medical Center have reprogrammed skin cells from an 82-year-old woman suffering from amyotrophic lateral sclerosis to generate first stem cells and then motor neurons. This is a significant advance which could...

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Detailed 3D image of Alzheimer's pathology

Category: Neuroscience

This three-dimensional reconstruction of an amyloid fibril (found at Discover) was created by Nikolaus Grigorieff and his colleagues at Brandeis University, by computer processing of a transmission electron cryomicroscopy image. It is the most detailed image yet of the abnormally...

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Neuroprotective effect of lifelong mental activity

Category: Medicine & Health

A new study, published today in the open access journal PLoS One, provides evidence that remaining mentally active throughout life reduces the rate of age-related neurodegeneration and may therefore stave off Alzheimer's Disease and other forms of dementia....

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Alois Alzheimer's first case

Category: History of neuroscience

On November 4th, 1906, during a lecture at the 37th Conference of South-West German Psychiatrists in Tubingen, the German neuropathologist and psychiatrist Alois Alzheimer (1864-1915, left) described "eine eigenartige Erkrankung der Hirnrinde" (a peculiar disease of the cerebral cortex). In...

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