CNS Diseases and Disorders

Neurotopia

Category archives for CNS Diseases and Disorders

Looks like yet another interesting toxin was found, this time in a venomous snail. This discovery comes from the lab of an old player in the field, who apparently discovered the conotoxin that is used in Prialt.

Amyotrophic Lateral Sclerosis is a devastating disease that claims the upper and lower motor neurons, and ultimately the lives of most patients within 3-5 years of diagnosis, usually from respiratory failure. Patients lose control of voluntary muscles as the pathways that innervate them degenerate. Lou Gehrig and Stephen Hawking are two famous ALS patients. Now…

Mixing Memory brings up some excellent points regarding mirror neurons in primates, and Frontal Cortex follows up with his thoughts. To both of them I say “bravo, but your skepticism probably doesn’t go far enough”. We give Rizzolatti et al too much credit with their conclusions. After all, they’ve only demonstrated the existence of mirror…

The difficulty with treating spinal cord injuries arises from a number of factors. Firstly there is the primary damage to the axons of the spinal cord itself, resulting in mechanical damage that can inhibit neurotransmission and transport of cellular material to and from the distal cord. The damaged cord must also compensate for secondary damage…

Shelley mentioned a study last week that suggested more and more young people are getting Parkinson’s Disease, and she wondered whether there was any utility in blaming our industrialized society based on the fact that certain compounds we produce can induce Parkinsonian symptoms. Let’s start by giving a brief overview of the systems involved before…

A highly conserved set of genes known as the sirtuin family are known to be activated by caloric restriction (CR) and extend the lifespan of a number of species. CR may also reduce the risk of Alzheimer’s Disease, and can prevent the formation of amyloid plaques in transgenic mouse models of AD. The question, then,…

…you might not know what to do you might have to think of how you got started sittin’ in your little room –The White Stripes