Neurotopia (version 2.0)

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The Evil Monkey has a Ph.D. in Neuroscience and is currently enjoying a bit of time off while waiting to hear about a new position. Come join this wayward neuroscientist as he struggles to find a career and get his life back in order. He is still not sure why he wrote this paragraph in the third person.

Disclaimer: The opinions on this blog do not represent any organization to which I may belong, or employers, or basically anybody but myself. So there.

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Alzheimer's Disease:

Oops! Memantine's actions really aren't all that and a bag of chips

Memantine is the most recent weapon in the fight against Alzheimer's. There's been a lot of hype surrounding the drug because.... The first-generation of compounds aimed to boost the brain's acetylcholine levels led to the development of drugs such as...

Posted on January 14, 2008 11:52 PM • 1 Comments • 0 TrackBacks

Alzheimer's Disease and risky sexual behavior: not quite a false alarm?

Abel got a badly worded email which made him worried that Alzheimer's may be caused by sexually transmitted diseases. Turns out he's not completely off the mark.

Posted on November 15, 2007 11:48 AM • 7 Comments • 0 TrackBacks

Promising Effects of Statins on Alzheimer's Pathology

Finally we get some data on changes in AD pathology with statin use! Statins are taken for lowering cholesterol, but they have other beneficial effects such as modulating inflammatory responses. Thus, they could prove beneficial in the treatment of AD...

Posted on August 29, 2007 3:50 PM • 2 Comments • 0 TrackBacks

Eat chana masala to prevent Alzheimer's!

Yes, that title is a bit ostentatious. But the foods we eat contain many compounds that can be beneficial to brain health. One strategy for optimizing our brains for long-term peak performance is to identify these compounds and discover how...

Posted on July 18, 2007 3:03 PM • 2 Comments • 0 TrackBacks

The Basics of Menopause and Hormone Therapy III: Cognitive Consequences

Postmenopausal women frequently complain about problems with attention and concentration, and increased forgetfulness. Controlled studies of the cognitive effects of menopause and HRT, however, have been controversial.

Read on »

Posted on July 6, 2007 1:05 AM • 3 Comments • 0 TrackBacks

SIRT1 Pathways and the Prevention of Alzheimer's Pathology

A highly conserved set of genes known as the sirtuin family are known to be activated by caloric restriction (CR) and extend the lifespan of a number of species. CR may also reduce the risk of Alzheimer's Disease, and can...

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Posted on July 9, 2006 1:47 AM • 3 Comments • 0 TrackBacks

Following up on Leptin

Pure Pedantry found this paper on leptin's effects in the hippocampus, and then went on to wonder I have never heard of a link between leptin and memory. They also make this link between ABeta mice and leptin. ABeta is...

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Posted on June 14, 2006 2:04 PM • 4 Comments • 0 TrackBacks