Mad scientists, start drooling

The future is arriving fast. Here are the instructions for assembling a $500 home molecular biology laboratory — you can do it! And it’s getting cheaper all the time!

The widespread and increasing availability of second-hand professional laboratory equipment or inexpensive new commercial surrogates means that it is now unchallenging to set up a fully functional molecular laboratory for less than $500 in equipment costs. Coupled with the presence of sources for all reagents and supplies needed in formats that are safe for general use, the work presented here demonstrates that capacity to set up functional molecular biology teaching modules is well within the reach of even the smallest educational facilities. When coupled with outsourced PCR product Sanger sequencing available from commercial sources at prices approaching $5/reaction, the capacity of such “home labs” to start undertaking research of real potential scientific value–such as surveys of microbial biota in unusual environments–at negligible costs should not be underestimated. Similarly, the potential for setting up labs of this type for medical applications in emerging countries may be worth considering. While current best methods have moved to real-time and array-based high throughput, contamination resistant methods, the methods demonstrated here were “state of the art” for clinical and research molecular diagnostics in the Western world only some 15 years ago.

Hmmm. The kids have flown, I’ve got more space than we know what to do with…maybe this summer I should tinker with setting up something like this.

(Also on FtB)