Molecular Biology

Pharyngula

Category archives for Molecular Biology

I’ve been guilty of teaching bean-bag genetics this semester. Bean-bag genetics treats individuals as a bag of irrelevant shape containing a collection of alleles (the “beans”) that are sorted and disseminated by the rules of Mendel, and at its worst, assigns one trait to one allele; it’s highly unrealistic. In my defense, it was necessary…

Techniques to go with the tools

So you read that cool summary of how to build a molecular biology lab for $500. But wait, you don’t know what you’d do with the mobio toys! Here’s how to correct that: go to a workshop. THE MICHAEL SMITH LABS AND ADVANCED MOLECULAR BIOLOGY LAB PRESENTS OUR MOLECULAR BIOLOGY WORKSHOPS 2012 WINTER/SPRING Session. ONE…

Mad scientists, start drooling

The future is arriving fast. Here are the instructions for assembling a $500 home molecular biology laboratory — you can do it! And it’s getting cheaper all the time! The widespread and increasing availability of second-hand professional laboratory equipment or inexpensive new commercial surrogates means that it is now unchallenging to set up a fully…

My turn at Skepticon

Yeah, I gave a talk at Skepticon like several other rascals here at Freethoughtblogs. Now, even if you didn’t make the pilgrimage to Springfield, Missouri, you can watch it too. It’s a straight science talk with several swipes at creationism, so unfortunately, I don’t think it will make any ice cream salesmen cry. (Also on…

This is an article about cephalopods and eye evolution, but I have to confess at the beginning that the paper it describes isn’t all that interesting. I don’t want you to have excessive expectations! I wanted to say a few words about it, though, because it addresses a basic question I get all the time,…

How to examine the evolution of proteins

In my previous post, I described the misguided approach Gauger and Axe have taken to criticizing evolution, and one of the peculiarities of their criticism is that they cited another paper by a paper by Carroll, Ortlund, and Thornton which traced (successfully) the evolutionary history of a class of proteins. Big mistake. As I pointed…

The epigenetics miracle?

Jerry Coyne is mildly incensed — once again, there’s a lot of recent hype about epigenetics, and he doesn’t believe it’s at all revolutionary. Well, I’ve written about epigenetics before, I think it’s an extremely important subject central to our understanding of development, and…I agree with him completely. It’s important, we ought to spend more…

That’s not hyperbole. I really mean it. How else could I react when I open up the latest issue of Bioessays, and see this: Cephalopod origin and evolution: A congruent picture emerging from fossils, development and molecules. Just from the title alone, I’m immediately launched into my happy place: sitting on a rocky beach on…

A little cis story

I found a recent paper in Nature fascinating, but why is hard to describe — you need to understand a fair amount of general molecular biology and development to see what’s interesting about it. So those of you who already do may be a little bored with this explanation, because I’ve got to build it…

The saga of Junk DNA

So you’re tantalized by this strange obsession creationists have with junk DNA. It offends them mightily, I think because they find comfort in the idea that everything in the universe must have a purpose, because if it doesn’t, maybe that means they are nothing more than spots of dandruff on a dead rock hurtling blindly…