Molecular Biology

Pharyngula

Category archives for Molecular Biology

Mad scientists, start drooling

The future is arriving fast. Here are the instructions for assembling a $500 home molecular biology laboratory — you can do it! And it’s getting cheaper all the time! The widespread and increasing availability of second-hand professional laboratory equipment or inexpensive new commercial surrogates means that it is now unchallenging to set up a fully…

My turn at Skepticon

Yeah, I gave a talk at Skepticon like several other rascals here at Freethoughtblogs. Now, even if you didn’t make the pilgrimage to Springfield, Missouri, you can watch it too. It’s a straight science talk with several swipes at creationism, so unfortunately, I don’t think it will make any ice cream salesmen cry. (Also on…

This is an article about cephalopods and eye evolution, but I have to confess at the beginning that the paper it describes isn’t all that interesting. I don’t want you to have excessive expectations! I wanted to say a few words about it, though, because it addresses a basic question I get all the time,…

How to examine the evolution of proteins

In my previous post, I described the misguided approach Gauger and Axe have taken to criticizing evolution, and one of the peculiarities of their criticism is that they cited another paper by a paper by Carroll, Ortlund, and Thornton which traced (successfully) the evolutionary history of a class of proteins. Big mistake. As I pointed…

The epigenetics miracle?

Jerry Coyne is mildly incensed — once again, there’s a lot of recent hype about epigenetics, and he doesn’t believe it’s at all revolutionary. Well, I’ve written about epigenetics before, I think it’s an extremely important subject central to our understanding of development, and…I agree with him completely. It’s important, we ought to spend more…

That’s not hyperbole. I really mean it. How else could I react when I open up the latest issue of Bioessays, and see this: Cephalopod origin and evolution: A congruent picture emerging from fossils, development and molecules. Just from the title alone, I’m immediately launched into my happy place: sitting on a rocky beach on…

A little cis story

I found a recent paper in Nature fascinating, but why is hard to describe — you need to understand a fair amount of general molecular biology and development to see what’s interesting about it. So those of you who already do may be a little bored with this explanation, because I’ve got to build it…

The saga of Junk DNA

So you’re tantalized by this strange obsession creationists have with junk DNA. It offends them mightily, I think because they find comfort in the idea that everything in the universe must have a purpose, because if it doesn’t, maybe that means they are nothing more than spots of dandruff on a dead rock hurtling blindly…

I’ve been giving talks at scientific meetings on educational outreach — I’ve been telling the attendees that they ought to start blogs or in other ways make more of an effort to educate the public. I mentioned one successful result the other day, but we need more. I give multiple reasons for scientists to do…

How to afford a big sloppy genome

My direct experience with prokaryotes is sadly limited — while our entire lives and environment are profoundly shaped by the activity of bacteria, we rarely actually see the little guys. The closest I’ve come was some years ago, when I was doing work on grasshopper embryos, and sterile technique was a pressing concern. The work…