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jake-head-shot.jpgJake Young is a MD/PhD student at Mount Sinai School of Medicine in NYC getting a PhD in Behavioral Neuroscience. He holds a BS and MS in Biological Sciences from Stanford University. If a volcano were to erupt Pompei-style in Central Park, his body would be preserved in a scoliotic posture over his lab desk. Archeaologists would later conclude that he spent most of his day training rats to perform tricks, until he went blind building electrical equipment by hand using a dissecting microscope. But, still, he died happy...because science is cool.

Pure Pedantry is a blog about science -- social sciences and otherwise -- as well as academic and scientific culture. No one can live on science alone, so I also like to dwell on pop culture, periodically explore the humanities, and indulge in other types of geeky goodness.

DISCLAIMERS: 1) Jake Young is not a licensed physician (yet). He is merely a medical student. The information published on this site is not intended for use in medical decision-making. Please seek advice from a licensed, medical professional before making any health decisions. 2) The opinions expressed are my own. They do not represent the views of SEED magazine or the educational establishments I currently attend or attended in the past.

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Steroid abusers get big gums, guns

Category: Medicine
Posted on: July 5, 2006 9:39 PM, by NotoriousLTP

Anabolic steroid abusers get gingival overgrowth (that would be big gums), or so says this study in the Journal of Periodontology:

Researchers found that prolonged use of anabolic androgenic steroid (AAS) is closely associated with significant levels of gingival enlargement, according to a new study published in the Journal of Periodontology.

Gingival overgrowth is a condition in which the gingival tissues become swollen and grow over the teeth. Overgrown gums make it easier for bacteria found in plaque to accumulate and attack supporting structures of the teeth, potentially leading to severe periodontal infection.

"It was found that AAS abusers had statistically significant levels of gingival enlargement compared to non-users, requiring a gingivectomy for many cases," explains Onur Ozcelik, DDS, PhD, Faculty of Dentistry, Cukurova University, Department of Periodontology, Adana, Turkey. "Although it has been reported that many of the adverse effects of AAS abuse are fully reversible within several months after the cessation of the drug, it is not known if gingival enlargement would also regress after the withdrawal of AAS."

Researcher also found that gingival inflammation was higher in the AAS user group compared to the non-AAS users. "Further studies are required to find out if increased gingival scores in the user group are a direct effect of AAS or if the inflammation is a result of compromised oral hygiene due to gingival enlargement," said Ozcelik.

...

People taking AAS without medical supervision should be informed of the adverse effects and strongly encouraged to begin a cessation program. (Emphasis mine.)

God, you know with all the horrendous acne, violent mood swings, inability to lift my arms above my head, and testicular cancer, I almost forgot how much it would suck to have big gums.

How is research like this getting paid for!?

For pictures of gingival overgrowth check here. (I didn't have to heart to copy them...they are kind of gross.)

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Comments

1

I knew Bubba from Forrest Gump was on the juice!

Posted by: Bob3732 | July 6, 2006 12:40 AM

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