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jake-head-shot.jpgJake Young is a MD/PhD student at Mount Sinai School of Medicine focusing in Neuroscience. He is due to graduate in 2032. He received a BS and a MS in Biological Sciences from Stanford University -- where he spent most of his time drinking heavily and building vegetable catapults instead of learning information that would now be eminently useful. When he is not failing terrifically to perform his sworn duties, he enjoys watching bad movies, ethnic food, and running.

Pure Pedantry is a blog about science -- social sciences and otherwise -- as well as academic and scientific culture. No one can live on science alone, so I also like to dwell on pop culture, periodically explore the humanities, and indulge in other types of geeky goodness.

Jake is joined periodically by two wonderful guest bloggers: Kara Contreary and Kate Seip. See the About Page.

DISCLAIMERS: 1) Jake Young is not a licensed physician (yet). He is merely a medical student. The information published on this site is not intended for use in medical decision making. Please seek advice from a licensed, medical professional before making any health decisions. 2) The opinions expressed are my own or those of my co-bloggers. They do not represent the views of SEED magazine or the educational establishments we currently attend.

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August 31, 2006

Would you bronze your daughter's first poop? Tom Cruise would

Category: Pop culture

I don't even want to know how he got it: Tom Cruise and Katie Holmes have yet to show their baby daughter off in public, but eager fans were given an unusual preview with the chance to see a bronze...

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Genetics does not play as large a role in longevity as previously thought

Category: Aging and Longevity

I have posted before about how I think that the role of genetics, at least in popular culture, has been overemphasized. Rather, the really interesting and important parts of genetics are the ways in which your genes interact with environmental...

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August 30, 2006

Kyra Phillips creates a whole new Situation Room

Category:

Kyra, Kyra, Kyra... Note to self: turn off mic in the john. Kyra Phillips, anchor of CNN's "Live From...," unwittingly upstaged President Bush's speech in New Orleans with on-the-air analysis of her husband and the marriage of her brother --...

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Reminder: Submit to the Synapse #6

Category: The Synapse (a neuroscience carnival)

The Synapse #6 is being hosted on The Mouse Trap on Sunday, September 3rd. Submission guidelines here....

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Ethical Stem Cells Hyped?

Category:

Those of you who read an earlier post here noted that I was somewhat skeptical of the technical aspects of the so-called ethical stem cells. I felt that there were several technical hurdles that had to be surmounted before this...

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August 29, 2006

Must Read: The History of the Neuron Doctrine

Category: Neuroscience

The Neurophilosopher has a fabulous long post on the discovery of the neuron as the fundamental unit of the nervous system. I would note when you get to the part about Ramon y Cajal that his picture of the neurons...

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Discussion on Means and Ends

Category: Science politics

There is an excellent discussion on Prometheus about whether it is OK to distort the means of science to justify certain ends. Money quote: This is of course an issue much broader than climate change, and at its core is...

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August 28, 2006

Molecular pathway for hairiness identified

Category: Biology

Wouldn't we all like to know how to control hairiness? Women complain that they have too much, and spend half their lives eradicating the little bastards. Men have too little on the tops of their heads, and, let us say,...

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Encephalon #5 is up

Category: Carnivals

Encephalon #5 is up at Developing Intelligence....

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Tom Cruise Linked to Valerie Plame?!

Category:

You be the judge? Meanwhile, Cruise has been busier pushing Scientology than anyone knew. According to a just-declassified State Department schedule, Cruise visited then-Deputy Secretary of State Richard Armitage on June 13, 2003, just an hour after Armitage had met...

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Suggestions on Raising Pluto's Self Esteem

Category: Astronomy

So Pluto is no longer a planet (totally destroying everything I learned in elementary school), and I get the feeling the little guy is bummed out about it. I have a list of suggestions of things Pluto can do to...

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Questions about Jared Diamond's Collapse

Category: Environment

First, I would note that I think Jared Diamond is a fabulous scientist, and a brilliant man. His work in Guns, Germs and Steel was genius, and well qualifies him in my book as someone we should all listen to....

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August 27, 2006

Support the Animal Enterprise Terrorism Act

Category: Science policy

This is completely unacceptable: The constant calls, the people frightening his children, and the demonstrations in front of his home apparently became a little too much. Dario Ringach, an associate neurobiology professor at the University of California at Los Angeles,...

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No new cortical neurons in humans, BrdU and C14 analysis

Category: Neuroscience

I have talked before about evidence that there is no new neurogenesis in the adult cortex, but that paper used stereological techniques. A new paper in PNAS shows a more direct method to demonstrate that there are no newly created...

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August 23, 2006

Ethical Stem Cells?

Category: Embryonic Stem Cells

The press is all in a tizzy about so-called ethical stem cells, but this still indicates a really limited understanding of how embryonic stem (ES) cells work. (Frankly, if I had a dollar for every time I read bad reporting...

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I Want a T-shirt

Category:

I don't really know why, but for some reason this Flickr page makes me want to buy an "I [Brain] Cognitive Science" T-shirt. Brainy women are hot. Hat-tip: Mind Hacks....

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Crazy Videos of Ants

Category: Aminals

Did you know that ants snap their mandibles together so fast that they can throw themselves in the air? Check out this (click on the video link to watch it): When trap-jaw ants need to get out quick, they use...

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August 22, 2006

Required Reading

Category:

OmniBrain has a funny post on the secret of antigravity. The Neurophilosopher has a interesting post on how neuropathic pain could be treated with menthol, which activates cold receptors. The American Scientist Online publishes an interview with Marc Hauser on...

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Deletion mouse shows resistance to depression, similarity to mice treated with antidepressants

Category: Depression

Before, I talk about a mouse model that is resistant to depression, I think I had better talk about mouse models of depression so that everyone is on the same page. If you ask a nonscientist whether they think there...

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Can you sell something that violates conservation of energy?

Category: Physics

Right: An Irish company has thrown down the gauntlet to the worldwide scientific community to test a technology it has developed that it claims produces free energy. The company, Steorn, says its discovery is based on the interaction of magnetic...

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Dark matter exists, so we got that going for us

Category: Physics

Dark matter definitely exists: New observations of a great big cosmic collision provide the best evidence yet that invisible and mysterious dark matter really does exist. The collision, between two huge clusters of galaxies, is the "most energetic cosmic event,...

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BMI is not a good predictor of cardiovascular risk

Category: Obesity and Heart Disease

BMI or Body Mass Index is a measure of obesity that is used to approximate the health problems associated with being overweight. It is really easy to calculate. The formula for it is weight in kilograms divided by height in...

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August 21, 2006

Shameless Self Promotion: OLIG2 is a schizophrenia susceptibility gene

Category: Schizophrenia

OK, so I am not actually on this paper, but my boss is. It is also what I am doing my thesis on, so I thought I might mention it. The article is entitled "Convergent evidence that oligodendrocyte lineage transcription...

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Look to the babies for (math) wisdom

Category: Neuroscience

Babies smarter than average high school student: In a discovery that could shed light on the development of the human brain, University of Oregon researchers determined that infants as young as six months old can recognize simple arithmetic errors. The...

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People actually eat fish from the Hudson!?

Category:

I run down the Hudson a lot, and I am utterly amazed by people who fish there. It just seems like a unpleasant place to fish. But I had no idea that people were actually eating what they caught: For...

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What a fabulously annoying invention

Category: Technology

The Clocky Alarm Clock is an alarm clock designed to flee the scene when it wakes you up so that you have to go search for it to turn it off: Clocky (patent pending) is an alarm clock that runs...

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Synapse #5

Category: The Synapse (a neuroscience carnival)

Synapse #5 is up at Retrospectacle. The next Synapse is going to be hosted at The Mouse Trap on September 3rd. Submission info here....

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August 20, 2006

It's Income, Not Inequality

Category: Public Health

I found this article interesting, if for no other reason than people seem to be misunderstanding what it says and what it does not say. The article by Leigh and Jencks for the Kennedy School of Government is entitled "Inequality...

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August 18, 2006

Ruminations from Douglas Adams

Category:

Quotes of the Day from Mostly Harmless by Douglas Adams: "I know that astrology isn't a science,' said Gail. "Of course it isn't. It's just an arbitrary set of rules like chess or tennis or, what's that strange thing you...

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Is Arabic Language Instruction Biased?

Category: Academic Bias

Is Arabic language instruction biased? Frank Salameh, writing in RCP, says yes (but not in the way that you would think):...

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Reading for Today

Category:

Interesting reading for today: The Neurocritic has a very good article on cognitive effects of socio-economic status. There are three important points: 1) the effects are not genetic, 2) there are a variety of different cognitive consequences, and 3) the...

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Lawrence Krauss on the Kansas School Board

Category: Culture War

Lawrence Krauss has this essay in the NYT where he argues against irrational exuberance about the recent school board elections in Kansas and the ouster of some Creationist school board members. Money quote: I have recently been criticized by some...

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LTP-related genes are clustered in genome

Category: Neuroscience

LTP activated genes are clustered on chromosomes -- or so says some work by Park et al in JBC. LTP -- or long-term potentiation -- is a process by which synaptic strength -- the ability of one neuron to talk...

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Partial Spinal Regeneration in Rats Using a Two Part Process

Category: Regeneration

This is rather clever. Houle et al at Case Western show in the Journal of Neuroscience that you can use a bacterial enzyme called chondroitinase to degrade scars in spinal cord lesions and enable regeneration of axons. Just for background,...

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August 17, 2006

A Personal Explanation for Light Blogging

Category:

I haven't been posting much because I am defending my Quals today. 81 slides...I am so the Power Point God. UPDATE: Triumph! I have passed. One more hurdle between me and occupational recognition overcome. And, yes, 81 slides was a...

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August 16, 2006

Ancient Super-Whale Ate Sharks For Breakfast

Category:

How fantastic is this: A 25-million-year-old whale fossil from southeastern Australia has revealed a bizarre early type of 'baleen' whale. The creature was an ancient cousin of our modern blue whales and humpbacks, but it was hardly a gentle giant...

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August 14, 2006

Encephalon #4 is Up

Category: Carnivals

Encephalon #4 is up at the Neurocritic....

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A Whole New Creative Way for Humans to Suck: Bark Poaching

Category:

Every time I think the human species has fully exploited all the ways one species can suck donkey balls -- found just every reason for all the other species be like "Yeah, we're not with them." -- we find newer,...

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Planetary Idol: Is Pluto a Planet?

Category: Astronomy

Scientists meet in Prague to discuss whether Pluto is a planet: Nearly 2,500 astronomers from 75 countries gathered in Prague Monday to come up with a universal definition of what qualifies as a planet and possibly decide whether Pluto should...

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August 11, 2006

Some confounds in gender differences in cognition: handedness, sexual preference, hormones

Category: Gender

Keeping to my week long theme of gender differences in cognition (here and here), here is an article by Diane Halpern in eSkeptic. It not only summarizes a lot of what is known about gender differences (even though it is...

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August 10, 2006

What explosives were to be used on the UK planes?

Category: Terrorism

Watching the news coverage today, I found myself wondering what type of explosive the terrorists were trying to use on the UK planes. I did a web search, and many news services are speculating that the chemical in question could...

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Amuse Yourselves with this Poem...

Category: Poems

...it is one of my favorites. Snow The room was suddenly rich and the great bay-window was Spawning snow and pink roses against it Soundlessly collateral and incompatible: World is suddener than we fancy it. World is crazier and more...

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Out

Category:

Hi all, Blogging is going to be sporadic til Monday. I am in transit to see the Fam until then. (Don't even get me started on the pooch screw that was security at JFK this morning. Have you ever seen...

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August 9, 2006

40 Percent of World of Warcraft Players Addicted, Sex Insufficient Motivation to be Exposed to Sunlight

Category: Video Games

Apparently the sexual drive is insufficient at motivating many people to leave their apartments: Having treated all types of addictions for more than 15 years, Orzack says there's little difference between drug use, excessive gambling and heavy game playing. And...

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Discoverer of Van Allen Belts Dead at 91, Van Halen Unfortunately Still Alive and Kicking

Category: Astronomy

Why do we lose all the good ones? Physicist James A. Van Allen, a leader in space exploration who discovered the radiation belts surrounding the Earth that now bear his name, died Wednesday. He was 91. The University of Iowa,...

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Debunking the Upper Tail: More on the Gender Disparity

Category: Gender

Earlier this week I argued that the gender differences in cognition, while real, are not substantial enough to explain gender disparities in science. We talked about the work of Janet Hyde; it shows that -- contrary to the popular conception...

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August 8, 2006

So...many...Pandas...

Category: Aminals

That's a lot of Panda: A giant panda in China has given birth to the heaviest cub born in captivity after the longest period in labor and elsewhere twin pandas each gave birth to twins, Xinhua news agency reported. Six-year-old...

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Universe discovered to be older than previously stated, brings statements about Universe's prenuptial virginity into question

Category: Astronomy

It's all the lying that really gets me: The universe could be 2 billion years older than thought, according to a new report by an international team of astronomers. The scientists have found that a nearby galaxy is 15% farther...

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Wheeee!

Category: Technology

Look, an Israeli inventor has patented the McDonald's playland as a way to escape fires: A specialised emergency truck would carry an extendible boom that could be raised to a window in a burning building. Jaws at the top of...

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There is a manatee in the Hudson

Category: Aminals

There is a manatee in the Hudson; which is interesting because I had always associated the Hudson with industrial waste, bad smells, the periodic dead person, and kayakers who seem to have no problem floating amongst those things: Over the...

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August 7, 2006

Litigation Activate: Ultrasound Edition

Category: Law

Yikes. You just can't win with embryos: Pasko Rakic of Yale Medical School in New Haven, Connecticut and his team were similarly scanning experimental mice, to help inject dye into embryos. When later studying the brain development of these mice,...

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Excellent Review on Epigenetics as a Means of Soft-Inheritance

Category: Evolution

The traditional Darwinian view of evolution holds that evolution occurs through the selection of the most successful members of a group. Each member of the group is stable over its lifetime. This view was later modified to include the idea...

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Bedbugs supplant nocturnal micturition as primary reason not to bring women home

Category:

Bedbugs say "I'm back baby!": After waking up one night in sheets teeming with tiny bugs, Josh Benton could not sleep for months and kept a flashlight and can of insecticide with him in bed. "We were afraid to even...

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Synapse #4

Category: The Synapse (a neuroscience carnival)

Wasn't here to mention it yesterday, but the Synapse #4 is available at Neurotopia. The next Synapse is on August 20th at Retrospectacle. Submission guidelines here....

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Combating Injury with Information: Gender Differences in Cognition

Category: Gender

I was at a wedding this weekend, and I was getting in one of those conversations that drunk people get into at weddings: what are the gender differences in cognition? OK, so maybe you don't get into conversations like this...

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August 4, 2006

Blogging Forecast: Light to Nonexistent

Category:

Sorry folks. Heading to a wedding for the weekend. Blogging light to nonexistent til Monday morning. Have a good weekend!...

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August 3, 2006

New Hypothesis: Parkin causes Parkinson's Disease via Downregulation of Akt Signaling

Category: Neurodegenerative disease

Neurodegenerative diseases, including Parkinson's, were for many years regarded as exclusively diseases of molecular crud. You would look at brains of patients with Alzheimer's and Parkinson's patients and notice that there were all these aggregates of protein crud forming in...

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Reminder: Submit to the Synapse #4

Category:

The Synapse #4 is being hosted by Neurotopia on Sunday. He asks that you get your submissions in by midnight on Saturday. Information for submitters is available here....

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A Personal Story (Stolen) about the Heat Wave and Medicine

Category: Medicine

It is like sweat and balls hot out, so I have a little personal story -- or rather my Dad's personal story -- to tell about heat waves. My Dad is an Emergency Room doctor, and he has been working...

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August 2, 2006

Biometric Soda Machine?

Category:

Some students at UCSD have too much time on their hands: A group of grad students at the University of California, San Diego (UCSD) are in the process of creating what one of the students calls the "most over-designed soda...

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Biggest Object in Universe

Category:

The biggest object in the Universe is glimpsed, and everyone is surprised: An enormous amoeba-like structure 200 million light-years wide and made up of galaxies and large bubbles of gas is the largest known object in the universe, scientists say....

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August 1, 2006

Scientist to Men: Don't sleep over

Category: Sleep

Muahaha. It has now been proven that men should not sleep over: If you have ever thought you were stupid to sleep with someone, consider this. Sharing your bed could actually make you stupid if you are a man -...

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Floyd Landis is Busted

Category: Sports Doping

As some of you may have noticed, I have been keeping up with the science of Floyd Landis's failed drug test in a rather long post here. In the post, I mentioned that there is another test besides the Testosterone...

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Carnivals

Category: Carnivals

I have been falling down on the job on my carnivals updating. Encephalon #3 is up at Thinking Meat. Grand Rounds is up at Inside Surgery....

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Not your normal Myers-Briggs

Category:

You've taken a Myers-Briggs personality inventory before right? They are usually strings of yes-or-no questions that give you a result like INTJ or ENTP. These kinds of tests populate the internet, and for what they are worth they are fun...

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Adult neuronal and oligodendrocyte stem cell identified

Category:

This is huge. Jackson et al. have identified that the adult stem cell in the human brain for both neurons and oligodendrocytes are the PDGFR-alpha expressing cells and that PDGF-AA causes proliferation of these cells and a shift towards the...

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