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jake-head-shot.jpgJake Young is a MD/PhD student at Mount Sinai School of Medicine focusing in Neuroscience. He is due to graduate in 2032. He received a BS and a MS in Biological Sciences from Stanford University -- where he spent most of his time drinking heavily and building vegetable catapults instead of learning information that would now be eminently useful. When he is not failing terrifically to perform his sworn duties, he enjoys watching bad movies, ethnic food, and running.

Pure Pedantry is a blog about science -- social sciences and otherwise -- as well as academic and scientific culture. No one can live on science alone, so I also like to dwell on pop culture, periodically explore the humanities, and indulge in other types of geeky goodness.

Jake is joined periodically by two wonderful guest bloggers: Kara Contreary and Kate Seip. See the About Page.

DISCLAIMERS: 1) Jake Young is not a licensed physician (yet). He is merely a medical student. The information published on this site is not intended for use in medical decision making. Please seek advice from a licensed, medical professional before making any health decisions. 2) The opinions expressed are my own or those of my co-bloggers. They do not represent the views of SEED magazine or the educational establishments we currently attend.

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History of Alois Alzheimer

Category: HistoryMedicineNeurodegenerative diseaseNeuroscience
Posted on: November 8, 2006 10:48 AM, by Jake Young

I meant to post this early, but the Neurophilosopher has an excellent history of Alois Alzheimer, for whom the disease is named:

On November 25th, 1901, a 51-year-old woman named Auguste Deter (below right) was admitted to the hospital, and was examined by Alzheimer. Deter at first presented with impaired memory, aphasia, disorientation and psychosocial incompetence (which was, at that time, the legal definition of 'dementia'); her condition gradually worsened, and she started losing other cognitive functions and experiencing hallucinations. Because of her age, Deter was diagnosed with presenile dementia; today, the diagnosis would be early-onset Alzheimer's Disease, which is defined as development of the condition before the age of 65.

augusted.jpgDeter died in April 1906, aged 55. By that time, Alzheimer had left Frankfurt, and was working under Emil Kraepelin at the Royal Psychiatric Clinic in Munich. Hearing of Deter's death, he requested from Sioli, the director of the Frankfurt institution where Deter had been, that her medical records be sent to him.

...

Ironically, it appears that Deter's death was caused not by the pathologies now associated with Alzheimer's Disease but rather by arteriosclerosis (hardening of the arteries) in the brain.

Read the whole thing.

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