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jake-head-shot.jpgJake Young is a MD/PhD student at Mount Sinai School of Medicine focusing in Neuroscience. He is due to graduate in 2032. He received a BS and a MS in Biological Sciences from Stanford University -- where he spent most of his time drinking heavily and building vegetable catapults instead of learning information that would now be eminently useful. When he is not failing terrifically to perform his sworn duties, he enjoys watching bad movies, ethnic food, and running.

Pure Pedantry is a blog about science -- social sciences and otherwise -- as well as academic and scientific culture. No one can live on science alone, so I also like to dwell on pop culture, periodically explore the humanities, and indulge in other types of geeky goodness.

Jake is joined periodically by two wonderful guest bloggers: Kara Contreary and Kate Seip. See the About Page.

DISCLAIMERS: 1) Jake Young is not a licensed physician (yet). He is merely a medical student. The information published on this site is not intended for use in medical decision making. Please seek advice from a licensed, medical professional before making any health decisions. 2) The opinions expressed are my own or those of my co-bloggers. They do not represent the views of SEED magazine or the educational establishments we currently attend.

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How Freezing Arthropods taught me how to freeze embryos

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Posted on: December 19, 2006 10:37 AM, by Jake Young

They must have interesting Christmas parties:

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A tiny, six-legged critter that suspends all biological activity when the going gets tough may hold answers to a better way to cryopreserve human eggs, researchers say.

Tardigrades, also called water bears, can survive Himalayan heights or ocean depths as long as they have moisture.

When they don't, they produce a sugar, trehalose, slowly dehydrate and essentially cease functioning until the rain comes, says Dr. Ali Eroglu, reproductive biologist and cryobiologist at the Medical College of Georgia.

Tardigrades are not alone in their amazing ability to outlast adverse conditions. A type of brine shrimp, often called a sea monkey, comes back to life with water. The Baker's yeast Dr. Eroglu uses when he bakes bread with his children does as well. Similarly arctic wood frogs use the sugar, glucose, to tolerate frigid temperatures until the summer thaw.

While humans don't naturally produce trehalose, researchers think they can use it to safely preserve human eggs - and those of endangered species - giving better options to young women facing cancer therapies that may leave them infertile and others who simply want to delay reproduction.

Reporter: So what do you do?
Scientist: I study how arthropods survive being frozen.
Reporter: What department are you in?
Scientist: Human reproductive medicine...yeah...we're kind of lax about that sort of thing...

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