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jake-head-shot.jpgJake Young is a MD/PhD student at Mount Sinai School of Medicine in NYC getting a PhD in Behavioral Neuroscience. He holds a BS and MS in Biological Sciences from Stanford University. If a volcano were to erupt Pompei-style in Central Park, his body would be preserved in a scoliotic posture over his lab desk. Archeaologists would later conclude that he spent most of his day training rats to perform tricks, until he went blind building electrical equipment by hand using a dissecting microscope. But, still, he died happy...because science is cool.

Pure Pedantry is a blog about science -- social sciences and otherwise -- as well as academic and scientific culture. No one can live on science alone, so I also like to dwell on pop culture, periodically explore the humanities, and indulge in other types of geeky goodness.

DISCLAIMERS: 1) Jake Young is not a licensed physician (yet). He is merely a medical student. The information published on this site is not intended for use in medical decision-making. Please seek advice from a licensed, medical professional before making any health decisions. 2) The opinions expressed are my own. They do not represent the views of SEED magazine or the educational establishments I currently attend or attended in the past.

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Oligodendrocytes:

Neuron to Glia Synapses on Axons?

Category: Neuroscience

I posted a couple months ago about neuron to glia (in this case oligodendrocyte) synapses in the hippocampus, and how researchers had shown that these synapses were capable of LTP. This was an example of two themes 1) the brain...

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Scienceblogs welcomes OmniBrain

Category: Oligodendrocytes

Scienceblogs welcomes OmniBrain, a neuroscience blog that I am quite fond of. I am particularly fond of this cartoon, which has to be the funniest one ever made about oligodendrocytes. Granted that is a small group, but still...a very good...

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Watch Oligodendrocytes Move in Vivo!

If you remember back from when I was at the Society for Neuroscience, I saw a talk by Bruce Appel where he showed videos of oligodendrocytes migrating and myelinating in the zebrafish. Oligodendrocytes are the myelin forming cell in the...

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Shameless Self Promotion: OLIG2 is a schizophrenia susceptibility gene

Category: Schizophrenia

OK, so I am not actually on this paper, but my boss is. It is also what I am doing my thesis on, so I thought I might mention it. The article is entitled "Convergent evidence that oligodendrocyte lineage transcription...

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Adult neuronal and oligodendrocyte stem cell identified

This is huge. Jackson et al. have identified that the adult stem cell in the human brain for both neurons and oligodendrocytes are the PDGFR-alpha expressing cells and that PDGF-AA causes proliferation of these cells and a shift towards the...

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Neuron to Glia Synapses

Category: Oligodendrocytes

Now I study oligodendrocyte development, and if you ask me they are a truly unappreciated cell type. Here is yet one more piece of evidence: synapses have been detected between neurons and oligodendrocytes in CA1 of the hippocampus AND these...

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