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jake-head-shot.jpgJake Young is a MD/PhD student at Mount Sinai School of Medicine focusing in Neuroscience. He is due to graduate in 2032. He received a BS and a MS in Biological Sciences from Stanford University -- where he spent most of his time drinking heavily and building vegetable catapults instead of learning information that would now be eminently useful. When he is not failing terrifically to perform his sworn duties, he enjoys watching bad movies, ethnic food, and running.

Pure Pedantry is a blog about science -- social sciences and otherwise -- as well as academic and scientific culture. No one can live on science alone, so I also like to dwell on pop culture, periodically explore the humanities, and indulge in other types of geeky goodness.

Jake is joined periodically by two wonderful guest bloggers: Kara Contreary and Kate Seip. See the About Page.

DISCLAIMERS: 1) Jake Young is not a licensed physician (yet). He is merely a medical student. The information published on this site is not intended for use in medical decision making. Please seek advice from a licensed, medical professional before making any health decisions. 2) The opinions expressed are my own or those of my co-bloggers. They do not represent the views of SEED magazine or the educational establishments we currently attend.

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Learning and Memory:

The Best Way to Study: Practice Tests

I remember when I was studying for Step I of the medical Boards. Step I is the first of three very large tests that you have to take to become a doctor. This first test comprises everything you learn in...

Pavlovian-Instrumental Transfer in Humans

In behavioral neuroscience, we use a lot of animal models. We assume that these animal models have features that are the same or similar to features of humans. However, it is always reassuring when someone gets around to proving that...

Article on exercise and cognition has correct facts, wrong interpretation

NYTimes Science section, why do you make me so mad? Gretchen Reynolds published an article in the Times on cognitive improvements associated with exercise, and I would like to use it to make a point about how science journalism often...

The Amnesia Drug: Frightening but Interesting

We tend to think of memories in the brain once they are consolidated as relatively stable things. For example, you don't tend to think of any active biochemical process being necessary to maintain long-term memories. This is almost an intuitive...

Gesticulation improves learning

Vindication at last. I catch a lot of hell because I tend to talk with my hands. However, Susan Wagner Cook for the University of Chicago has shown that when teaching math problems kids who repeat the hand gestures of...

Inverse relationship between working memory and neurogenesis

This is interesting. Researchers at Columbia have established that restricting neurogenesis in the hippocampus improves working memory: New research from Columbia University Medical Center may explain why people who are able to easily and accurately recall historical dates or long-ago...

Patients with hippocampal amnesia lack imagination

We have been talking about this paper in PNAS around the lab, so I thought I would share. Hassabis et al, publishing in PNAS, have shown that patients with hippocampal damage lack the ability to imagine novel situations. This is...

More Evidence of LTP in vivo

I wrote earlier this week about evidence from electrode arrays that LTP occurs in vivo in behaving rats ("Rats, you behave!"). The paper showed that if you use an avoidance learning paradigm you can detect LTP in the hippocampus after...

LTP observed from learning paradigm in vivo

My suspicion is that the people who know about neuroscience read the title of this and said: "Wow, Jake, there's a shocker. Tell us something we didn't know." Everyone else probably said: "Guh?" Therefore, I should probably explain why I...

All-Nighter Ho! -- Culture Wars: David Brooks on Gender Differences

I must admit that in general I like David Brooks. He seems to lack the stridency of many pundits, and I don't generally like people who shout. He also tends -- like Walter Bagehot -- not to think that people...

Leptin Injection Improves Memory in Mice

This paper shows that leptin injections into the hippocampus improves memory in a T-maze footshock avoidance and step down inhibitory avoidance tasks. It caught my eye because I just finished a course in behavioral neuroscience, but I have never for...

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