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scientificactivistprofile.gif A postdoc by day and a scientific activist by night, Nick Anthis isn't letting his research in protein structure and function get in the way of defending scientific and social progress.

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biochemistry:

On Mimicking Phosphotyrosine

Category: structural biology

Why glutamate is generally not a suitable mimic for phosphorylated tyrosine.

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Two New Papers on Integrin Activation

Category: integrins

My first first-author paper and another that I contributed to shed light on the important biological process of integrin activation.

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2009 Nobel Prize in Chemistry: The Ribosome

Category: Nobel Prize

The prize will be shared equally between Venkatraman Ramakrishnan, Thomas Steitz, and Ada Yonath "for studies of the structure and function of the ribosome."

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Why Swine Flu Is Resistant to Adamantane Drugs

Category: structural biology

All H1N1 swine flu isolates tested to date are resistant to adamantane-based drugs. This post explains the origin of this resistance in light of what we know about the structure and function of influenza proteins.

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Fine-Tuning Cell Adhesiveness

Category: integrins

The cell adapts to constantly changing conditions by controlling the adhesiveness of the integrins.

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2008 Nobel Prize in Chemistry: GFP

Category: Nobel Prize

"for the discovery and development of the green fluorescent protein, GFP"

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Do You Want to Be Able to Crap Gold?

Category: chemistry

That might not be possible, but ingesting isotopically-enriched food would make your waste even more valuable.

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An Integrin Is Identified as a Co-Receptor for HIV

Category: HIV/AIDS

Scientists identify the alpha-4 beta-7 integrin as a co-receptor for HIV, offering a potential new drug target.

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Integrin Phosphorylation as an Off Switch for Integrin Activation

Category: Life of Nick

A tiny modification can make a big difference in proteins involved in cell adhesion and migration.

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My Second Scientific Paper: Matrix Protease Activity in Tumor Cell Invasion

Category: Life of Nick

The second paper from my undergraduate work at Texas A&M University was recently published in Molecular Cancer. The abstract can be found here, and the pdf of the full paper here. Molecular Cancer is an open access journal, so a...

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The Structure of the Living Cell

Category: structural biology

Oxford's Iain Campbell discusses the past and future of structural biology.

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My First Scientific Paper: The Stabilization of Blood Vessels by Protease Inhibitors

Category: Life of Nick

My first appearance in the peer-reviewed scientific literature provides an opportunity to learn a little bit about blood vessel development.

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2006 Nobel Prize in Chemistry: Eukaryotic Transcription

Category: Nobel Prize

The 2006 Nobel Prize in Chemistry has been awarded to Roger Kornberg for his work on elucidating the molecular basis of transcription in eukaryotes.

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2006 Nobel Prize in Physiology or Medicine: RNA Interference

Category: biochemistry

The 2006 Nobel Prize in Physiology or Medicine was announced this morning, with one half going to Andrew Fire and the other half to Craig Mello, both for the discovery of RNA interference (RNAi). The discovery of RNAi added a...

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Fantastical Fridays: Genetic Engineering's Next Challenge - The Smiley Face

Category: Fantastical Fridays

Genetic engineering holds a great deal of promise, but it can only be used on things that are "alive". Still, scientists have found other ways to make the stuff of genes, DNA, come alive in more artistic ways.

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Fantastical Fridays: NMR Goes Natural, Baby!

Category: Fantastical Fridays

In NMR, bigger really is better, at least when it comes to magnetic field strength, and the entire field has in some ways become one big manhood size-measuring contest. One group, though, reported earlier this year in Nature Physics that sometimes it may be better to just go natural. Forget about all of the high-tech magnets--just use the big one right under your feet!

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Nobel Laureate Robert Huber to Give Talk at Oxford

Category: events

This is a plug for an event that the Oxford University Biochemical Society is putting together. This Monday, June 12th, at 4:00 pm the Oxford University Biochemical Society will be hosting a talk by Nobel Laureate Robert Huber in the...

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