“The layman always means, when he says “reality” that he is speaking of something self-evidently known; whereas to me it seems the most important and exceedingly difficult task of our time is to work on the construction of a new idea of reality.” -Wolfgang Pauli
On the surface, it shouldn’t appear to make all that much difference to the Universe whether a particle has a spin in half-integer intervals (±1/2, ±3/2, ±5/2) or in integer intervals (0, ±1, ±2). The former is what defines fermions, while the latter defines bosons. This hardly seems like an important distinction, since intrinsic angular momentum is such a nebulous property to our intuitions, unlike, say, mass or electric charge.
Yet this simple, minor difference carries with it two incredible consequences: one for the existence of distinct particles for antimatter and one for the Pauli exclusion principle, that are required for matter as we know it to be. Without these differences, and without these rules, it’s simply a matter of fact that the atoms, molecules and living things we see today wouldn’t be possible to create.