“When you listen to a lecture, you should not have any idea of yourself. You should not have your own idea when you listen to someone. Forget what you have in your mind and just listen to what he says. To have nothing in your mind is naturalness. Then you will understand what he says. But if you have some idea to compare with what he says, you will not hear everything; your understanding will be one-sided; that is not naturalness.” -Shunryu Suzuki
When we take a look at the Universe, there are a whole slew of things we can measure: densities, masses, couplings, and so on. When these measurable quantities arise from the same physical mechanism, we expect them to be closely related; when they don’t, we expect them to be dissimilar. Yet sometimes, unrelated things are alike in a seeming coincides, while related things are vastly different in an unexplained hierarchy. In cases like this, we look for physical explanations.
Are we going about things all wrong in doing so, though? There may be a physical explanation for such fine-tunings, but it may also be the case that the Universe is simply unnatural in a variety of regards. But if unnaturalness reigns, then even the best science in the Universe may be unable to answer, even in principle, the simple questions of how certain quantities got the values that they have.