Over at Evolgen, RPM has posted the seventh installment of his series on detecting natural selection, a piece on nucleotide polymorphism and selection. As always, it is worth checking out. For those that missed the earlier pieces, here is RPM’s summary with links:
The introduction can be found here. The first post described the organization of the genome, and the second described the organization of genes. The third post described codon based models for detecting selection, and the fourth detailed how relative rates can be used to detect changes in selective pressure. The fifth post dealt with classical population genetics methods for detecting selection using allele and genotype frequencies. The sixth post described how to calculate nucleotide sequence polymorphism.