Others have mentioned Jerry Coyne’s shredding of Behe’s Edge of Evolution in The New Republic. I’d just like to highlight this paragraph as it more or less summarizes everything that Coyne has to say:
In the end, The Edge of Evolution is not an advance or a refinement of the theory of intelligent design, but a retreat from its original claims–an act of desperation designed to maintain credibility in a world of scientific progress. But it is all for nothing, because Behe’s new theory remains the same old mixture of dead science and thinly disguised theology. There is no evidence for his main claim of non-random mutation, and scientists have plenty of evidence against it. His arguments against the Darwinian evolution of complex organisms are flawed and misleading. And there is not a shred of evidence supporting his claim that the goal of evolution is intelligent life. In contrast to the feast of evidence that nourishes evolutionary theory, Behe gives us an empty plate.
After Kitzmiller v. Dover it appears that ID might be going out with a whimper.