genetic distance
razib | January 26, 2010One of the more substantive consequences of the powerful new genomic techniques has been in the area of ancient DNA extraction and analysis. The Neandertal genome story is arguably the sexiest, but closer to the present day there've been plenty of results which have changed the way we look at the past. The input of genetics has basically demanded a revision of the contemporary consensus of the origins of the Etruscans which emerged from archaeology. Though certainly ancestry and genetic relationship are informative, ancient DNA has also given us windows into the change of function and a…
razib | August 29, 2009Dienekes points me to a new paper, European Population Genetic Substructure: Further Definition of Ancestry Informative Markers for Distinguishing Among Diverse European Ethnic Groups. You've seen this song & dance before:
Population substructure in JapanPopulation substructure of Mexican MestizosEuropean population substructureGenetic Map of East AsiaThe genetics of Fenno-ScandinaviaFinns as European outliersUyghurs are hybridsGenetic structure of Eastern European populationsGenetic map of Europe; genes vary as a function of distance More genetic maps of EuropeHuman population structure…
razib | July 30, 2009An ancestry informative marker set for determining continental origin: validation
and extension using human genome diversity panels:
Results
In this study, genotypes from Human Genome Diversity Panel populations were used to further evaluate a 93 SNP AIM panel, a subset of the 128 AIMS set, for distinguishing continental origins. Using both model-based and relatively model-independent methods, we here confirm the ability of this AIM set to distinguish diverse population groups that were not previously evaluated. This study included multiple population groups from Oceana, South Asia, East…
razib | May 15, 2009Genome-wide Insights into the Patterns and Determinants of Fine-Scale Population Structure in Humans:
Studying genomic patterns of human population structure provides important insights into human evolutionary history and the relationship among populations, and it has significant practical implications for disease-gene mapping. Here we describe a principal component (PC)-based approach to studying intracontinental population structure in humans, identify the underlying markers mediating the observed patterns of fine-scale population structure, and infer the predominating evolutionary forces…
razib | May 5, 2009In the comments below on the post on human population structure there was some request for a bigger global perspective. Below the fold I've placed a table with FST values which compare each population to the other. This an older population genetic statistic derived from the work of Sewall Wright, but you are almost certainly familiar with the talking point that "85% of variation is within races, and only 15% between." That is an FST insight. The higher the FST the greater the proportion of genetic variation which can be attributed to between population differences, so it serves as a rough…