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Terra Sigillata

musings on medicines from the Earth

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JJA%20UMich%2065px%20wide.jpg Abel Pharmboy is the nom de plume of an academic researcher and educator who holds a PhD in Pharmacology. He writes on natural product drugs and dietary supplements, academic career development, medical journalism and, occasionally, making and listening to music and wine appreciation for the monetarily-challenged.

You can learn quickly the distinction between the fields of Pharmacology, Pharmacognosy, Pharmacy, the Pharmaceutical Sciences by clicking on the hyperlinks. You can learn more about the author here.

"Why Terra Sigillata?" will tell you about the origin of the blog name.

Please feel free to contact me off-blog by e-mail to abelpharmboy (at) gmail (dot) com.

Please read the DISCLAIMER for details on the blog's intended audience, advertising and comment policy, and how not to use the information presented herein.


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March 31, 2007

Blogger's code of conduct suggested after death threats

Category: Blogging community

Death threats against a tech blogger cause Tim O'Reilly and friends to suggest that we are responsible for not only our content, but the content of our comment threads as well.

Read on »

March 30, 2007

The Friday Fermentable: Wine Quips

Category: The Friday Fermentable

The meaning of Merlot to Utahans, and who is Fran Liebowitz anyway???

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Important point for patients on the withdrawal of pergolide (Permax)

Category: Drug safety

You may have read that pergolide (Permax), a drug used to treat Parkinson's disease, has been withdrawn voluntarily from the US market due to its causal association with heart valve abnormalities. I hope to have time later to discuss why...

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March 27, 2007

High school science project takes down Big Pharma

Category: Chemistry

A few years ago, GlaxoSmithKline marketed Remifemin brand of black cohosh extract from their consumer products division as a hormone-free alternative in managing menopausal symptoms. But after reports surfaced that black cohosh might be associated with cases of liver damage,...

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March 26, 2007

Derivative of the natural product, himbacine, shows promise in anticoagulation therapy

Category: Botanical/Herbal Medicines

Results from major US cardiology meeting on a semi-synthetic derivative of a compound from Australian magnolia bark.

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March 25, 2007

On being thankful

Category: Pediatric health

Docs have a million of these kinds of stories, but pediatrician Dr Clark Bartram at Unintelligent Design put up a particularly moving reflection on a recent case....

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March 24, 2007

More health news from Canada

Category: Cancer

For your Saturday morning reading pleasure, here are two articles following up on my dichloroacetate (DCA) and bogus internet pharmacy death posts this week. Each was recommended by my clandestine operative from the Great White North, PharmCanuck: Canadian cancer society...

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March 23, 2007

The Friday Fermentable: A Pinot Noir Revelation with Erleichda

Category: The Friday Fermentable

Guest-blogger Erleichda returns with a blind tasting of Pinot Noir, a column he wrote in November that I overlooked in my e-mail queue. Forty lashes with a grapevine!

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March 22, 2007

Larry (Bud) Melman: character and comedian, but pharma shill, too?

Category: Humor

Former Parke-Davis employee and late night character dies at 85.

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More dangers of internet drug purchasing

Category: Drug safety

OmniBrain's Sandra Kiuwe points out the drawbacks of responding to the "buy tramadol, buy Viagra, buy Vicodin" internet gambit.

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March 20, 2007

Nature remains the source of 70% of prescription drugs

Category: Pharmaceuticals

So say the American elder statesmen of natural products in the 2007 update of their periodic review of the subject to be published in the 23 March issue of the Journal of Natural Products. Yet only two major US pharmaceutical companies maintain dedicated natural product drug discovery efforts.

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March 19, 2007

Four days, four dichloroacetate (DCA) newspaper articles

Category: Cancer

My blog buddy Orac at Respectful Insolence has a superb post today following up on his continuous coverage of dichloroacetate and two posts I had recently on local coverage in the Edmonton Journal of this unapproved, experimental compound. As an...

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March 17, 2007

Edmonton pharmacist asked to stop selling dichloroacetate (DCA)

Category: Cancer

From the same reporter at the Edmonton Journal who brought us yesterday's DCA article comes news of a Canadian pharmacist who has been providing patients with physician-prescribed dichloroacetate.

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March 16, 2007

Local look at dichloroacetate (DCA) hysteria

Category: Cancer

A Canadian reporter digs into the dichloroacetate misrepresentation.

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If an MD-stock analyst warns that cancer drug prices are too high, does anyone hear?

Category: Pharmacoeconomics

This week has seen the launch of a new health blog by the Wall Street Journal. While I don't hold the highly conservative views of the WSJ editorial pages, I have found the paper one of the best international sources...

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March 14, 2007

Newsweek covers evolution; Begley online today

Category: Biology

The new issue of Newsweek (19 Mar 2007) carried a surprise for me: former Wall Street Journal health reporter, Sharon Begley, has moved back to the magazine. In fact, Begley wrote this week's excellent discussion and cover story on the...

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March 13, 2007

Complementary medicine at Australian infertility clinics

Category: Botanical/Herbal Medicines

How might chasteberrry treat infertility if it also makes one chaste???

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March 12, 2007

Daylight-saving time

Category: Stuff I don't know about

Read the post on DST at Cognitive Daily.

Read on »

March 10, 2007

For the locals: Bull City Headquarters opens today

Category: The Old North State

Since many homers read Terra Sig instead of my local interest blog, here's news on today's inaugural activities at our new community space, Bull City Headquarters (BCHQ)....

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March 9, 2007

Notable notes for 9 March 1957

Category: Blogging community

On this day in 1957, A magnitude 9.1 earthquake shook the Andreanof Islands in Alaska, the second strongest quake in U.S. history (although Alaska would not become the 49th state until more than a year later), generating a tsunami that...

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March 8, 2007

Curcumin intervention trial against precursor lesions of colon cancer in smokers

Category: Botanical/Herbal Medicines

Systematic testing of the potential use of this poorly-absorbed natural product.

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March 7, 2007

Raw garlic or garlic supplements lack beneficial effects on LDL-cholesterol

Category: Botanical/Herbal Medicines

While spending so much time last week on the issue of conscientious objection by pharmacists, I overlooked the 26 February publication in Archives of Internal Medicine of a very well-designed clinical trial to test the hypothesis that garlic/garlic supplements lower...

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March 6, 2007

How might antioxidant supplements increase all-cause mortality?

Category: Non-herbal supplements

If the data are true, what does this imply?

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March 5, 2007

pH meter recommendations?

Category: The Working Scientist

I've never used the blog for this purpose, but why not? The benchtop pH meter I purchased when starting the Pharmboy laboratory a number of years ago is beginning to have electronics problems (it's an old Fisher AccuMet of some...

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March 2, 2007

Oath of a pharmacist and code of ethics

Category: Pharmacy

For those who have been asking over the last couple of days, here are the oath of a pharmacist as recited at US colleges of pharmacy and a code of ethics adopted in 1994 by the then-American Pharmaceutical Association (now...

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March 1, 2007

Conscientious objection by health professionals: day two

Category: Bioethics

Yesterday's discussion of a pharmacist's right to refuse filling prescriptions based on moral or legal grounds generated some great discussion. I appreciate the thoughtful discussion of the commenters as well as two posts on the topic by Prof Janet Stemwedel....

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