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Terra Sigillata

musings on medicines from the Earth

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JJA%20UMich%2065px%20wide.jpg Abel Pharmboy is the nom de plume of an academic researcher and educator who holds a PhD in Pharmacology. He writes on natural product drugs and dietary supplements, academic career development, medical journalism and, occasionally, making and listening to music and wine appreciation for the monetarily-challenged.

You can learn quickly the distinction between the fields of Pharmacology, Pharmacognosy, Pharmacy, the Pharmaceutical Sciences by clicking on the hyperlinks. You can learn more about the author here.

"Why Terra Sigillata?" will tell you about the origin of the blog name.

Please feel free to contact me off-blog by e-mail to abelpharmboy (at) gmail (dot) com.

Please read the DISCLAIMER for details on the blog's intended audience, advertising and comment policy, and how not to use the information presented herein.


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May 29, 2007

Former Chinese FDA director sentenced to death

Category: Drug safety

A harsh response to bribes, food and drug safety lapses.

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Black cohosh and liver damage: how relevant?

Category: Botanical/Herbal Medicines

We've discussed previously the use of herbal extracts from black cohosh (Actea racemosa) for relief from hot flashes and other vasomotor symptoms of menopause and perimenopause. A clinical trial in Annals of Internal Medicine last December, showed that one black...

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May 28, 2007

Remembrance

Category: Personal

It doesn't take a hero to order men into battle. It takes a hero to be one of those men [and women] who goes into battle. - Norman Schwarzkopf Superb Memorial Day posts today from Orac at Respectful Insolence and...

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May 27, 2007

Safer source of glycerin

Category: Drug safety

Biodiesel production also provides a home-grown source of glycerin/glycerol.

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May 26, 2007

Remembering my blog namesake

Category: Pharmacology

Seventy-nine years ago today marked the passing of Dr John Jacob Abel, known as the American father of Pharmacology. Beyond his work on epinephrine, insulin, and devising a dialysis machine, Abel founded the departments of pharmacology at the University of...

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May 24, 2007

Diethylene glycol in Panamanian toothpaste

Category: Drug safety

I seem to have missed this NYT article over last weekend. Following from the continuing appearance of diethylene glycol in glycerin imported from China, yet another consumer product is found to be adulterated, again in Panama: Diethylene glycol, a poisonous...

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May 23, 2007

Arsenic: from drug to poison to drug again

Category: Cancer

The 2 May issue of the Journal of the National Cancer Institute has an interesting news article on the advancing use of arsenic trioxide against a variety of human malignanices, mostly cancers of the blood. The medical uses of arsenic...

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May 19, 2007

ASCO abstracts trigger trading

Category: Cancer

Despite disclaimers on the use of abstract contents, the release of ASCO's upcoming proceedings for their 1-5 June meeting has already caused interesting movement among investors.

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May 18, 2007

Sharks don't get cancer but do they get Salmonella poisoning???

Category: Non-herbal supplements

Actually, sharks do get cancer but a 15-year-old book by William Lane led people to think otherwise, launching investigation of shark cartilage as a source of antiangiogenic, anticancer compounds. While there is one promising shark cartilage extract (Neovastat) in clinical...

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May 16, 2007

Quick picks

Category: Drug safety

Assessing drug safety risks from Joseph and a survey of young docs' knowledge of dietary supplement regulation and adverse event reporting.

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May 13, 2007

Mother's Day reflections

Category: Personal

My Mom did all the great 'Mom' things and was also instrumental in my career choice. After I started grade school, she started feeling out a career in nursing by working as a secretary in the emergency room department of...

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May 12, 2007

CBC's 'The Current' on dichloroacetate (DCA)

Category: Alternative medicine

A Canadian radio program devotes 20 minutes this week to the conundrum surrounding the use and promotion of dichloroacetate (DCA) for the self-medication of cancer.

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May 11, 2007

Mannatech missteps in WSJ

Category: Alternative medicine

The practices of Mannatech distributors were the focus of a detailed article in this morning's Wall Street Journal by Suzanne Sataline. The Issue: Some consumers are using Mannatech nutritional supplements to seek relief from serious medical problems. The Background: The...

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May 9, 2007

Melamine and cyanuric acid chemistry lesson

Category: Diet and Health

Great science journalism from WaPo's David Brown.

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More on unsafe food additives

Category: Diet and Health

I'll have the stir-fried tofu with vegetables - hold the formaldehyde, please.

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May 8, 2007

Deadly cough syrup: simple, at-site detection of diethylene glycol and ethylene glycol

Category: Drug safety

FDA posts a paper describing a simple TLC method for saving lives from diethylene glycol adulteration.

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May 7, 2007

Who is most Abel?

Category: Pharmacology

To celebrate the 100th anniversary of the major pharmacology society, Nature reports that scientists are tracing their degrees of separation from my blog namesake and father of American pharmacology, John Jacob Abel.

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May 6, 2007

Deadly cough syrup: the real costs of cheap drug excipients

Category: Drug safety

New York Times reporters track a misrepresented pharmaceutical excipient from China, through Spain, to Panama where over 100 were killed last year from diethylene glycol poisoning. The article details the real costs of sourcing "cheap" food and drug ingredients from poorly regulated markets.

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May 4, 2007

The Friday Fermentable: Do you know how much you pour?

Category: The Friday Fermentable

As wine and beer glasses grow ever larger, are our habits of having one or two drinks a day for health benefits actually bordering on binge drinking?

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May 3, 2007

Another decimal point pet peeve

Category: Drug safety

Am I being too demanding or unreasonable in requesting a leading zero? To my aging eyes ".5 mg/mL" could be read as either 0.5 mg/mL or 5 mg/mL. Could this fact have been responsible for the ten-fold colchicine dosing error found responsible for three patient deaths in Oregon?

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Great professional development for K-12 science teachers

Category: K-12 education

BSCS in Colorado Springs offers two intensive summer institutes for science teachers: "Evolution Across the Sciences" and "Scientific Inquiry: Research & Practice"

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May 2, 2007

Weight loss drug mix-up - more risks using internet pharmacies

Category: Drug safety

If Ron Evans' PPAR-delta-activating drug makes it to market, one still has to be sure that pharmacies are filling the prescriptions with the correct pills.

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May 1, 2007

NCI features another natural product in clinical trials

Category: Clinical trials

What is it about T-cell lymphoma that attracts the development of HDAC inhibitors???

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FDA seeks comments on regulating "CAM products"

Category: Alternative medicine

Should the FDA exercise powers it already has instead of instigating a new class of "CAM products" that is certain to get caught up in a legal morass?

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