Terra Sigillata

Archives for March, 2008

In attempting to re-engage my academic brain stem, I’ve been doing a little continuing education the last couple of weeks at various forums hosted by the University-That-Tobacco-Built. Last week I had the pleasure of attending a forum of the Duke student organization, Women in Science and Engineering (WiSE), that featured four academic leaders (who were…

A paper in last month’s issue of Nature Reviews Drug Discovery reported that US drug approvals during 2007 were the lowest number since 1983. (17 new molecular entities and 2 biologicals; see this figure for 1996-2007 data.) The review cites increased regulatory action as a factor in this reduction, especially following high-profile post-marketing safety issues…

Only time for a short post today but many news outlets are just now picking up on a 12 March WaPo article by David Segal on the 10th anniversary of the US FDA approval of the erectile dysfunction drug, Viagra. As we noted in yesterday’s post, the active ingredient in Viagra, sildenafil, is so popular…

Blue Steel Hero

No, it’s not a song by Foreigner – these are the names of two products “promoted and sold over the Internet for the treatment of erectile dysfunction (ED) and for sexual enhancement.” In yet another instance of a trend that would be comical if not so serious, the US FDA has announced that “Blue Steel”…

Last week we spent some time discussing the shortcomings of the generic vs. brand name drug debate, focusing on an example of non-bioequivalence between the antidepressant Wellbutrin XL and its generic competitors. Three days later, I then received an e-mail from one John Procter about a movement to get Washington to move forward on the…

Saturday morning round-up

I usually don’t do these kinds of linkfests but we’re on the road for a Pharmboy family Easter weekend and there are a few items of interest that slipped through my fingers recently. Here are a few things that readers may enjoy this weekend: Bora’s blog gets its 1,000,000th visitor Go over and offer congratulations…

The safety and effectiveness of medicines and other health products is dependent upon their proper use, particularly the proper route of administration. There are reasons why products are labeled as “for topical use only” or “do not swallow” – two recent warnings from the US FDA illustrate these issues. Allergic Reactions with Use/Misuse of Denture…

Two political posts in two days. Apologies to those who come here for the science but these are the issues getting my attention and energy this week. Billy Bragg is a special guy in my life and this song from 2002 was particularly prescient. In memory of those lost in the 11 September attacks, the…

“Not this time.”

No matter who you support – wow.

This issue was brought up by my fellow blogger, Joseph at Corpus Callosum, following an article in yesterday’s LA Times. For those not familiar with the concept or countries other than the US where laws may differ, generic drugs are those with the same active chemical as the originally-approved “brand name” drug. The original drug…