Drug safety

Terra Sigillata

Category archives for Drug safety

The Dietary Supplement Health and Education Act of 1994 (DSHEA) allows herbal and non-herbal supplements to be sold in the US without demonstration of effectiveness or safety. Despite recent improvements in Good Manufacturing Practices required of supplement manufacturers, these products still pose significant risks to the population simply because the hands of regulatory authorities are…

Blue Steel Hero

No, it’s not a song by Foreigner – these are the names of two products “promoted and sold over the Internet for the treatment of erectile dysfunction (ED) and for sexual enhancement.” In yet another instance of a trend that would be comical if not so serious, the US FDA has announced that “Blue Steel”…

Last week we spent some time discussing the shortcomings of the generic vs. brand name drug debate, focusing on an example of non-bioequivalence between the antidepressant Wellbutrin XL and its generic competitors. Three days later, I then received an e-mail from one John Procter about a movement to get Washington to move forward on the…

The safety and effectiveness of medicines and other health products is dependent upon their proper use, particularly the proper route of administration. There are reasons why products are labeled as “for topical use only” or “do not swallow” – two recent warnings from the US FDA illustrate these issues. Allergic Reactions with Use/Misuse of Denture…

This issue was brought up by my fellow blogger, Joseph at Corpus Callosum, following an article in yesterday’s LA Times. For those not familiar with the concept or countries other than the US where laws may differ, generic drugs are those with the same active chemical as the originally-approved “brand name” drug. The original drug…

Just a hypothesis here. A vibrant, 55-year-old Denver-area furniture executive, Lesile Fishbein, is possibly near death according to The Denver Post: The bubbly Fishbein, one of the most recognizable faces in the metro area because of her television ads for her company, Kacey Fine Furniture, was admitted to Presbyterian/St. Luke’s Hospital for emergency treatment on…

DrugMonkey just had an interesting post about the potential influence of cocaine use trends following the 1986 death of Maryland college basketball player, Len Bias, just days after his being selected in the NBA draft by the Boston Celtics. DM’s post and the ensuing discussion got me thinking tonight about a variety of issues in…

[Note: I originally posted this last Thursday under another title but it got lost in other events of that day. As I find it ironic that Mr Comarow has been attacked by an alternative medicine practitioner and advocate, I find this story worthy of reposting.] A few weeks ago the skeptical blogosphere was up in…

For more details on this story, you can go to Mark Chu-Carroll, Orac, Mike the Mad Biologist, or the Autism Blog. I just wanted to share my personal views on the need for childhood vaccinations and support a public information campaign from the AAP. Until I started medical blogging, I had not realized quite how…

I’ll leave my neuropharmacology and neuroscience colleagues to comment in greater detail on this story (see earlier DrugMonkey post), but this report is just in from AP on Heath Ledger’s toxicology report: The cause of death was “acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam and doxylamine,” spokeswoman Ellen Borakove said…