Drug safety

Terra Sigillata

Category archives for Drug safety

Rise Up: Blogroll Amnesty Day

Yesterday was the 1st anniversary of Blogroll Amnesty Day, originally proposed by a reasonably prominent blogger who used the occasion to relieve himself of guilt when purging his blogroll and building back up only a list of those he reads regularly. I learned via my new homies, PhysioProf and DrugMonkey that Jon Swift and Skippy…

Yesterday, the FDA released a warning statement on an increasingly common mistake in the medically-unsupported practice of “chelation therapy” for autism: FDA notified healthcare professionals and patients about important safety information concerning Edetate Disodium. There have been cases where children and adults have died when they were mistakenly given Edetate Disodium instead of Edetate Calcium…

…there is a very colorful discussion thread of hangover remedies over at the WSJ Health Blog. Yesterday, Health Blog’s Jacob Goldstein briefly discussed a 2000 Annals of Internal Medicine paper on alcohol hangovers and remedies/prophylactic approaches. Despite all of the discussion, Goldstein also cites a 2005 systematic review in BMJ by Max Pittler and Edzard…

Yet another example in today’s press about dietary supplements contaminated, intentionally or accidentally, with prescription or unapproved drugs – in this case, anabolic steroids showing up in about 20% of supplements tested. I was asked by a major news organization if this is the first time that anabolic steroids have been found in supplements. Nope,…

Compounds in grapefruit juice inhibits an enzyme required for metabolism of nearly half of prescription drugs on the market. If you inhibit drug metabolism, would that allow you to take a lower (and cheaper) dose of one of those drugs, especially an expensive drug? That is the proposition of a company called Bioavailability Systems, featured…

As I sat to write a post this morning, I became more engaged in a story in the New York Times magazine by Dr Daniel Carlat entitled, “Dr. Drug Rep.” Joseph of Corpus Callosum recently commented here about being solicited to recommend fellow physicians in the local area and nationally who he perceived as “thought…

I wrote about the general issue of eyelash-enriching “cosmeceuticals” on my Terra Sigillata back in July. Increasing the number and thickness of eyelashes is not some hokey magical wish – it is a known side effect buried in the prescribing information for the prescription glaucoma drugs, bimatoprost (Lumigan®) and latanoprost (Xalatan®). Last Friday, the US…

Perhaps you’ve stumbled on this post late at night while tending to a child suffering from a cold. Well, I’ve been reading a fair bit lately about the 18-19 October meeting of the FDA’s joint meeting of their Nonprescription Drug and Pediatric Advisory Committees, trying to make sense about calls to restrict or prohibit the…

I’ve got to admit that I’ve really enjoyed reading Health Blog from the Wall Street Journal. Short, pithy, and great bites about health/pharma stories that make it into one of the best sources for news in the US (its op-ed page notwithstanding). So, I was tickled on Friday to see Health Blog interview AggravatedDocSurg. Little…

Why lay off 25% of the FDA

You read correctly. If the US Senate does not pass an FDA funding bill today, 2,000 employees, nearly one-quarter of the FDA staff, will be relieved of their duties. (There were 8,157 FDA employees in 2006 – source). The House has already passed the bill but there are concerns: Senate staffers were poring over the…