Pharmaceuticals

Terra Sigillata

Category archives for Pharmaceuticals

I was way behind on this story relative to the pharma blogosphere (John Mack’s Pharma Marketing Blog, Ed Silverman’s Pharmalot, and the WSJ Health Blog), but Montel Williams has created a PR disaster for Partnership for Prescription Assistance of the industry group, PhRMA (Pharmaceutical Research and Manufacturers of America). While promoting prescription assistance programs in…

Readers who are busting their butts doing basic and drug development research in pharmaceutical companies don’t need this kind of alleged behavior from upper management – from Jeanne Whalen at the Wall Street Journal (online yesterday and in today’s print edition) following up on a story first reported in the Journal on 24 May 2007:…

…is the title of a Newsweek article by Jonathan Alter posted online last night that draws more attention to the Medicare restriction on reimbursements for radioimmunotherapeutic (RIT) drugs used to treat lymphomas. Surgical oncologist, Orac, and I have spoken about this issue in the last few days. Alter admits his bias a bit, as he…

We wrote a few days ago on the disappointing discontinuation of Pfizer’s Exubera, the first inhaled insulin product. The always-insightful Dr Derek Lowe at In the Pipeline has an excellent commentary on this case, including his own take on the futility of putting lipstick on a pig: 1. Marketing isn’t everything. The next time someone…

Don’t Bogart My Insulin

Scott Hensley at the WSJ.com Health Blog had a banner day today with the sad withdrawal by Pfizer of their inhaled insulin product, Exubera. When I was a pharmacy professor in the mid-1990s, we shared Pharma’s optimism that an inhaled insulin product would be a godsend for diabetes patients who had to inject themselves with…

As we discussed here yesterday, ixabepilone, a semi-synthetic anticancer drug derived from a soil bacterium was up for review by the US Food and Drug Administration (FDA). Just over a half hour ago the manufacturer, Bristol-Myers Squibb, announced that the drug has indeed been approved for the treatment of advanced breast cancer. The drug will…

Breast Cancer Cure from Dirt?

Perhaps not a cure but certainly another critical tool in the anticancer armamentarium. If you’ve ever read our introduction to the left in my profile as to why this blog is called Terra Sigillata, you’d know that the first trademarked drug was dirt itself (or soil to be exact). Terra Sigillata was a special fatty…

The Pump Handle’s Liz Borowski put up a nice post summarizing the key points of the >400-page Food and Drug Administration Amendments Act of 2007 (H.R. 3580). Missing from the bill were any further restrictions on pharmaceutical direct-to-consumer (DTC) drug advertising – according to Liz, some drug safety advocates were calling for a complete ban…

Why lay off 25% of the FDA

You read correctly. If the US Senate does not pass an FDA funding bill today, 2,000 employees, nearly one-quarter of the FDA staff, will be relieved of their duties. (There were 8,157 FDA employees in 2006 – source). The House has already passed the bill but there are concerns: Senate staffers were poring over the…

Leukemia Drug Adulteration Chinese generic versions of the anticancer drugs, methotrexate and cytarabine hydrochloride, have been reported to be contaminated with an undisclosed substance according to several wire reports this morning. Several children in a Shanghai hospital were reported to suffer leg pain and difficulty walking after being injected with methotrexate. A common drug used…