Pharmacogenetics

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Category archives for Pharmacogenetics

The always-outstanding neuroblogger, SciCurious, put up an excellent post overnight on a presentation she saw at the current Annual Meeting of the Society for Neuroscience (SfN) in Chicago. Therein, she wrote about a poster presentation she saw on the relationship between iron, cholesterol, and Alzheimer’s disease. All was quite well until near the end of…

As noted in the previous post on the anticoagulant, Coumadin (warfarin), last week demonstrated how pharmacogenetic variations in drug metabolism and drug responses are giving rise to what is increasingly known as “personalized medicine.” In their second such warning last week, the US FDA alerted clinicians and the public to the use of codeine in…

Late last week saw two announcements from the US FDA on genetic issues in drug safety. The first of these addresses the prescribing guidelines for Coumadin, or warfarin. Coumadin is a “blood-thinner” (or anticoagulant) prescribed for conditions from heart valve and hip/knee joint replacements to pulmonary hypertension and following strokes due to inappropriate blood clotting.…