Pharmacology

Terra Sigillata

Category archives for Pharmacology

I just started receiving a bunch of Google referral hits from readers searching for a story about the US Federal Trade Commission apparently taking regulatory action against a church that is selling supplements claimed to exhibit anti-cancer activities. The article in question, “Tyrannical FTC Threatens Christian Church with Imprisonment for Selling Dietary Supplements,” was written…

I see you – I’ve been there. You’re sitting in the lab the day before New Year’s Eve looking at what you’ve done over the last year – or last six years – and thinking about how you’re ever going to turn this postdoc or extended grad school period into some gainful career. The economy…

A couple of colleagues turned me on the other morning to a press release by researchers at the University of Warwick who recently published in PNAS that their data apparently overturns the Meyer-Overton Rule regarding solubility of a compound in olive oil and its propensity for crossing biological membranes. I’m having trouble understanding exactly why…

Most people know of methadone as a long-term substitution therapy for people addicted to heroin, morphine, or other similar drugs called opiates or opioids. A good, free full-text description of methadone maintenance therapy (MMT) can be found in the 15 June 2001 issue of American Family Physician. Now, in the 1 August 2008 issue of…

This whole “cosmeceutical” thing probably shouldn’t be in “Medicine & Health” but we did call your attention to today’s news item back on 27 July 2007: Drug maker Allergan announced at a stock analyst’s meeting this afternoon that it is filing a New Drug Application (NDA) for a cosmetic form of its anti-glaucoma drug bimatoprost…

Our quick post yesterday cited Jonathan Alter’s Newsweek essay this week on the sad state of cancer research funding in the context of Hamilton Jordan’s recent death and Ted Kennedy’s recent glioblastoma diagnosis. Like many areas of US federal research funding, cancer research support has been flat under the Bush administration and, in fact, declined…

Sorry to get to this so late but I wanted to weigh on an excellent post from my cancer blogging colleague, Orac, the other day on the investigation of CAM therapies in cancer. The post covers a lot of ground, as expected from any of Orac’s exhaustive missives, but I wanted to focus on the…

Well, not only am I weaseling out of posting original content today but I’m going to direct you to an excellent repost by Bora Zivkovic at A Blog Around the Clock. I am often asked why plants expend the bioenergetic capital to synthesize secondary metabolites. In his post, Bora notes that the synthesis of capsaicin…

“. . .you got marijuana in my lead.” Two great tastes that do not go great together (with apologies). [Welcome Fark.com readers on 12 Oct 2008 - I comment on the recent story here and you can read our other posts on drugs of abuse here. Thanks for stopping by - APB] A concise but…

Actinomycin D was the first antitumor antibiotic isolated from Streptomyces parvallus cultures by the lab of 1952 Nobel laureate, Dr Selman Waksman, at Rutgers University. However, it took a young Chinese physician and the confidence in her by a future US Surgeon General for this natural product drug to positively impact the lives of children…