Physiology

Terra Sigillata

Category archives for Physiology

Who knew? As I am stuttering through recovery from LungMutiny2010, I am paying more attention to my diet. So, as I try to go out for my 10 min walk everyday, I still drink some sports drink – usually Gatorade made from the massive vat of powder you can buy here at Costco. We tend…

Have you ever taken one of the now-over-the-counter heartburn relief remedies like Tagamet, Zantac, or Pepcid? How about the beta-blocker atenolol (Tenormin) or metoprolol (Lopressor) for antihypertensive therapy, or the original less-selective beta-blocker propranolol (Inderal) for migraines, presentation anxiety or stage fright? If you answered yes to either question, you owe a debt of gratitude…

Although I saw this obituary over the weekend, I didn’t get to posting it until today. I was reminded by a local friend, an outstanding young scientist in her own right, of the impact that Dr Schanberg had made on so, so many lives in science, medicine, and our larger community. I only had the…

After writing this post, I came across Alex’s obituary and guestbook on Legacy.com. By all accounts, Alex was a great kid – loved and admired by many – an accomplished hockey player and musician with a love for the mountains. This could have been you or I, or worse, one of our own children. Breaking…

Welcome 4 March readers of The Daily Grail – please be sure to also click on the original post about the DMT article by my colleague, Laura Mariani. Thanks to Dave Munger & Co’s ResearchBlogging.org, I just found a fabulous neuroscience grad student blogger from Emory University: Laura E Mariani at Neurotypical? Doctor-to-be Mariani blogged…

The 2008 Nobel Prize in Physiology or Medicine has been split between the discoverers of two viruses of major pathophysiological importance. Half of the prize goes to German Dr prof Harald zur Hausen for his discovery of human papilloma virus as the cause of cervical cancer while the other half went to the French team…

A couple of colleagues turned me on the other morning to a press release by researchers at the University of Warwick who recently published in PNAS that their data apparently overturns the Meyer-Overton Rule regarding solubility of a compound in olive oil and its propensity for crossing biological membranes. I’m having trouble understanding exactly why…

The statin class of cholesterol-lowering agents is rich with history and lessons in the power of natural products, the potential of the prepared mind, and just how precarious the path of drug development can be. American Scientist, the official publication of the scientific research society Sigma Xi, hosts this issue an absolutely lovely article entitled,…

When I first heard that 24-year-old British singer-songwriter Amy Winehouse was hospitalized with early stage emphysema I said “what?” DrugMonkey, a drug-abuse research colleague, has a terrific post up now on the link between Winehouse’s crack cocaine use, possible genetic predisposition, and the emergence of early-onset emphysema. While sad to see a very young person…

Well, not only am I weaseling out of posting original content today but I’m going to direct you to an excellent repost by Bora Zivkovic at A Blog Around the Clock. I am often asked why plants expend the bioenergetic capital to synthesize secondary metabolites. In his post, Bora notes that the synthesis of capsaicin…