Toxicology

Terra Sigillata

Category archives for Toxicology

Today’s post comes to your courtesy of yet another of my revered Canadian colleagues: pharmacist Scott Gavura, author of the excellent Science-Based Pharmacy blog. Back in April, 21 Venezuelan polo horses from the Lechuza team died at the U.S. Open Polo Championship in Palm Beach County, Florida after being injected with a compounded supplement similar…

And the winner is. . .

Propofol. For further information and detailed background, please see our previous post on this injectable anesthetic agent known as propofol or Diprivan®. This L.A. Times article today also has a concise timeline of the events leading to the death of Michael Jackson

Artemisinin is a natural product isolated from the leaves of the annual wormwood, Artemisia annua. Used originally in Chinese herbal medicine, the pure compound is employed in Africa as an inexpensive antimalarial drug. In April, 2009, the multinational pharmaceutical company Novartis received FDA approval for a combination drug called Coartem®, comprised of the semi-synthetic artemisinin…

We’ve spoken here every few months about so-called natural dietary supplements being adulterated with prescription drugs used for similar indications. The most common of these of late have been erectile dysfunction supplements which have been repeatedly found to contain the active compounds present in prescription E.D. products such as Viagra and Cialis. The latest public…

While invoking my little-known real name, the ABC News Medical Unit shows its commitment to providing scientifically-objective and medically-valid commentary to the Michael Jackson circus. The post cited was from 26 June where I discussed the first Michael Jackson revelation that he had repeatedly been given the unusual opioid drug, meperidine, presumably for his chronic…

Judging from the press inquiries I’ve had since 5 am EDT today, expect today’s focus in the Michael Jackson case to be on the anesthetic drug, propofol (Diprivan®). Last evening, California nutritionist and registered nurse Ms Cherilyn Lee gave an interview to Campbell Brown on CNN (and this AP exclusive report) describing Michael Jackson’s repeated…

AOL’s celebrity gossip page TMZ.com was first yesterday to report Michael Jackson’s death, in part due to their direct line to one or more Jackson family members. They appear to have had another scoop today in referencing a family member who reported that Mr Jackson had received an injection of the opioid analgesic, Demerol (meperidine),…

My clinical counterpart, surgical oncologist Dr David Gorski, has an excellent post up today at Science-Based Medicine on the irresponsible and misleading information being provided at The Huffington Post during the current H5N1/2009 influenza (“swine flu”) outbreak. “The Huffington Post’s War on Medical Science: A Brief History” provides a cautionary tale for us in embracing…

Regular commenter and friend of Terra Sig, leigh (the path forward), let us know overnight that Florida State Veterinarian Dr Thomas J Holt officially confirmed that selenium overdose killed 21 Venezuelian polo horses in Wellington, Florida, on 19 April. An attempt by an Ocala, Florida, compounding pharmacy to reproduce an equine dietary supplement called Biodyl…

An interesting question arose the other day when we discussed the Key West acupuncturist who was diverting prescription drugs for personal use as well as in her practice. While we are not certain that the defendant put the cited muscle relaxants and anxiolytics in remedies doled out at her practice, we doubt that the demographic…