Category: Academia
Yes, friends: this year's Nobel Prize in Chemistry would not have been possible without the awesome power of natural products and the contributions of my natural products chemistry colleagues who provided Ramikrishnan, Steitz, and Yonath with the chemical tools for their work. "The ribosome is the target for about 50% of all antibacterial drugs to date, and the advent of high resolution structures of both ribosomal subunits has opened a large number of possibilities for [structure-based drug design] of new and effective drugs in the race against resistance development among bacterial pathogens."
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Posted by Abel Pharmboy at 8:02 AM • 2 Comments • 0 TrackBacks
Category: The Working Scientist
For those new readers with an interest in pharmaceuticals, be sure to bookmark Derek Lowe's In The Pipeline.
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Posted by Abel Pharmboy at 8:02 AM • 1 Comments • 0 TrackBacks
Category: The Awesome Power of Natural Products
For all of you parents of children with cancer, here's what your kids might be doing in 50 years.
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Posted by Abel Pharmboy at 1:02 PM • 2 Comments • 0 TrackBacks
Category: Drugs of Abuse
A repost of an early classic on real-time HPLC assessment of rave drug content by an Austrian research group funded to do so.
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Posted by Abel Pharmboy at 11:23 AM • 6 Comments • 0 TrackBacks
Category: Pharmacognosy
A research post from Laura Mariani's Neurotypical? reminds us how finding a common receptor mechanism for entheogens and hallucinogens reveals once again the awesome power of natural products in the discovery of the pathophysiology and pharmacotherapeutics of human diseases.
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Posted by Abel Pharmboy at 12:02 PM • 5 Comments • 0 TrackBacks
Category: Drugs of Abuse
My money, sadly, is on the hypothesis that the kid was trying to make meth.
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Posted by Abel Pharmboy at 8:51 PM • 12 Comments • 0 TrackBacks
Category: Science Comes Alive
Some visual coverage of the GFP story that I had missed.
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Posted by Abel Pharmboy at 4:46 AM • 0 Comments • 0 TrackBacks
Category: Academia
Chancellor of UNC-Chapel Hill joins the ranks of bloggers in a substantive way.
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Posted by Abel Pharmboy at 8:02 AM • 1 Comments • 0 TrackBacks
Category: Chemistry
Nature's gift of green fluorescent protein (GFP) from the jellyfish, Aequorea victoria, has always been important to me, personally and professionally. In fact, PharmGirl, MD, and I would have never met if not for this wonder macromolecule nor then would...
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Posted by Abel Pharmboy at 6:01 AM • 1 Comments • 0 TrackBacks
Category: Chemistry
Rodent data is suggestive of an extremely high level of safety of each compound when each is ingested alone. So why is the pet food contaminant now killing Chinese infants?
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Posted by Abel Pharmboy at 10:02 AM • 7 Comments • 0 TrackBacks
