Interview with Dr Ada Yonath, a 2009 Nobel Laureate in Chemistry
Category: Academia
"No one wanted to believe it because they didn't do it first"
Posted by Abel Pharmboy at 8:02 AM • 0 Comments • 0 TrackBacks
Terra Sigillata
musings on medicines from the Earth
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Abel Pharmboy is the nom de plume of a US state university educator and cancer researcher who holds a PhD in Pharmacology and Therapeutics and BS in Toxicology. He writes on natural product drugs and dietary supplements, issues of under-represented groups in the STEMM disciplines, science and medical journalism, the science and culture of North Carolina, Florida, and Colorado, making and listening to music and, with the help of his colleague, Erleichda, wine appreciation.
"Why Terra Sigillata?" will tell you more about the origin of the blog name.
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Chemistry:
Venkatraman Ramakrishnan, Thomas Steitz, and Ada Yonath win 2009 Nobel Prize in Chemistry
Category: Academia
Yes, friends: this year's Nobel Prize in Chemistry would not have been possible without the awesome power of natural products and the contributions of my natural products chemistry colleagues who provided Ramikrishnan, Steitz, and Yonath with the chemical tools for their work. "The ribosome is the target for about 50% of all antibacterial drugs to date, and the advent of high resolution structures of both ribosomal subunits has opened a large number of possibilities for [structure-based drug design] of new and effective drugs in the race against resistance development among bacterial pathogens."
Posted by Abel Pharmboy at 8:02 AM • 3 Comments • 0 TrackBacks
Derek Lowe (In The Pipeline) on ghostwriting and a real drug industry project meeting
Category: The Working Scientist
For those new readers with an interest in pharmaceuticals, be sure to bookmark Derek Lowe's In The Pipeline.
Posted by Abel Pharmboy at 8:02 AM • 1 Comments • 0 TrackBacks
Pediatric cancer patient checks in at age 55; beneficiary of Dr Charlotte Tan's actinomycin D work
Category: The Awesome Power of Natural Products
For all of you parents of children with cancer, here's what your kids might be doing in 50 years.
Posted by Abel Pharmboy at 1:02 PM • 3 Comments • 0 TrackBacks
Rave drug testing - public benefit?
Category: Drugs of Abuse
A repost of an early classic on real-time HPLC assessment of rave drug content by an Austrian research group funded to do so.
Posted by Abel Pharmboy at 11:23 AM • 6 Comments • 0 TrackBacks
Entheogen and hallucinogen, N,N'-dimethyltryptamine (DMT), identified as endogenous ligand for sigma-1 receptors
Category: Pharmacognosy
A research post from Laura Mariani's Neurotypical? reminds us how finding a common receptor mechanism for entheogens and hallucinogens reveals once again the awesome power of natural products in the discovery of the pathophysiology and pharmacotherapeutics of human diseases.
Posted by Abel Pharmboy at 12:02 PM • 5 Comments • 0 TrackBacks
"Pans" of hydrogen sulfide in San Jose teenager's death?
Category: Drugs of Abuse
My money, sadly, is on the hypothesis that the kid was trying to make meth.
Posted by Abel Pharmboy at 8:51 PM • 12 Comments • 0 TrackBacks
GFP slideshow at WSJ Health Blog
Category: Science Comes Alive
Some visual coverage of the GFP story that I had missed.
Posted by Abel Pharmboy at 4:46 AM • 0 Comments • 0 TrackBacks
Holden Thorp has a blog
Category: Academia
Chancellor of UNC-Chapel Hill joins the ranks of bloggers in a substantive way.
Posted by Abel Pharmboy at 8:02 AM • 1 Comments • 0 TrackBacks
The 2008 Nobel Prize in Chemistry - Glowing Accolades
Category: Chemistry
Nature's gift of green fluorescent protein (GFP) from the jellyfish, Aequorea victoria, has always been important to me, personally and professionally. In fact, PharmGirl, MD, and I would have never met if not for this wonder macromolecule nor then would...
Posted by Abel Pharmboy at 6:01 AM • 1 Comments • 0 TrackBacks
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