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Terra Sigillata

musings on medicines from the Earth

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Small profile avatar.jpg Abel Pharmboy is the nom de plume of a US state university educator and cancer researcher who holds a PhD in Pharmacology and Therapeutics and BS in Toxicology. He writes on natural product drugs and dietary supplements, issues of under-represented groups in the STEMM disciplines, science and medical journalism, the science and culture of North Carolina, Florida, and Colorado, making and listening to music and, with the help of his colleague, Erleichda, wine appreciation.

"Why Terra Sigillata?" will tell you more about the origin of the blog name.

Please read the DISCLAIMER for details on the blog's intended audience, advertising and comment policy, and how not to use the information presented herein.

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Health On Net

Pharmacology:

Are testosterone-deficient men responsible for shortages of a life-saving drug for women with breast cancer?

Category: Cancer

A physician's claim that "between 100 and 1,000 times more men than women" are on the aromatase inhibitor anastrozole raises questions behind a worldwide shortage of the drug. Are testosterone-deficient men in effect killing women with breast cancer?

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Did the patient fail the treatment or did we fail the patient?

Category: Biotechnology

Referring to clinical drug resistance or refractoriness to therapy as "the patient failed the treatment" is pissing me off this morning before I have my coffee.

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James Ray's Sedona sweat lodge stash: lessons in polypharmacy and endocrine pharmacology

Category: The American Southwest

The suitcase full of supplements and prescription drugs seized in the execution of a search warrant for James Arthur Ray's Arizona retreat hotel room provides a learning opportunity in endocrine pharmacology and drug prescribing for off-label uses.

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Sir John Crofton, TB combination therapy pioneer - a long and admirable life

Category: Infectious diseases

Denise Gellene in the New York Times is reporting this morning that Scottish physician, Sir John Crofton, passed away on 3 November at age 97. Crofton is best known for implementing a combination drug regimen to treat tuberculosis, the insidious...

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Lashing out at Latisse®

Category: Advertising

I never knew that Brooke Shields suffered from hypotrichosis.

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On the Origin of Witches, Broomsticks, and Flying

Category: The Awesome Power of Natural Products

You might not care to explain this in great detail to the kids or other Harry Potter fans, but the legend does in fact come from the awesome power of natural products.

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Venkatraman Ramakrishnan, Thomas Steitz, and Ada Yonath win 2009 Nobel Prize in Chemistry

Category: Academia

Yes, friends: this year's Nobel Prize in Chemistry would not have been possible without the awesome power of natural products and the contributions of my natural products chemistry colleagues who provided Ramikrishnan, Steitz, and Yonath with the chemical tools for their work. "The ribosome is the target for about 50% of all antibacterial drugs to date, and the advent of high resolution structures of both ribosomal subunits has opened a large number of possibilities for [structure-based drug design] of new and effective drugs in the race against resistance development among bacterial pathogens."

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Terra Sigillata cited as source for ABC News Michael Jackson story, sorta

Category: Shameless Self-Promotion

While invoking my little-known real name, the ABC News Medical Unit shows its commitment to providing scientifically-objective and medically-valid commentary to the Michael Jackson circus. Understandably, my exclamation of "Holy shit!" did not make the cut.

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Michael Jackson: Cherilyn Lee, Diprivan® (propofol), and Myers' Cocktail

Category: Alternative medicine

The late pop icon now appears to have requested a common, normally-safe intravenous anesthetic drug employed daily in outpatient surgical procedures. While not a common drug of abuse, Diprivan (propofol) can provide euphoric and anti-anxiety effects. Most relevant to the Jackson case, it can cause a rare side effect called "propofol-infusion syndrome" characterized by potentially fatal disturbances to cardiac pacing and rhythm.

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Pediatric cancer patient checks in at age 55; beneficiary of Dr Charlotte Tan's actinomycin D work

Category: The Awesome Power of Natural Products

For all of you parents of children with cancer, here's what your kids might be doing in 50 years.

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