Transcription and Translation

Archives for March, 2006

Weird things are afoot. It all started last time the crazies got together. We had our fill of food and drink. The conversation had turned to nudist beaches and the next thing we knew, books were stolen, a member was held up, and then German Nihilists hijacked the Boston bookclub blog. That’s when we thought…

So a couple of weeks ago, I wrote an entry about gender and science. I encourage you not only to read the post but also the comments. In that post I mentioned a 2003 Caltech postdoc survey that parsed some of the data by gender. Again I strongly recommend that you examine the raw data.…

Bravo Harvard

Harvard announced yesterday that it would waive tuitions for undergrads whose families earn less than $60,000 annually. From the Harvard Crimson: The newly expanded financial aid program, which will also reduce the contributions of families with annual incomes between $60,000 and $80,000, is expected to cover more than 1,500 students–nearly a quarter of the College–in…

NIH Budget

If you haven’t, go and read to evolgen’s entries on the Specter-Harkin Amendment that successfuly passed in the Senate to increase the NIH budget. Next up is the House. If you care about basic research in the biomedical sciences contact your local reps pronto. Contact Your US Representative about the NIH Budget (@ evolgen) The…

Update from Life Science Industry

Last night I was at another party in Cambridge, a good friend of mine is leaving Boston to go work for Pfizer in NYC. (Aside – why does it seem like anyone in Cambridge who is not a student or a professor, works for Biotech, Pharma or an IT start up?) In any case I…

The Sound and Taste of Revelation

Remember that special moment when everything changed. Were you listening to a particular song? Or was it some food? Well a couple of friends just posted about such associations. The first is from Tall Med Student, a former Harvard postdoc who is now a med student at the University of Calgary. In his ode to…

Computing Signals

OK after making fun of System Biologists out comes Peter Sorger’s latest paper in Cell. In this paper, Sorger’s team collected almost 8000 intracellular measurements (they collected some of the data directly and got the rest from the literature – I’ll have to check on that) plugged it into an algorithm or a … ……

Systems Biology DNA Prep???

(from the archives) Once upon a time, we made the necessary chemicals from scratch to purify DNA from bacterial cultures. These days, for a couple of dollars, you can get all the reagents you need all packaged in a nice box – these things are called commercial “kits”.

The van Oijen lab (here at HMS) had a nice paper in Nature where they indirectly observe single T7 DNA polymerase complexes copying DNA. How do they do it? One end of the DNA is fixed while the other side is coupled to a bead that can be visualized. A laminar flow is applied to…

Organelle Quiz

Want to be a Cell Biologist? Take a look at this phase image of a rat hepathocyte (liver cell) that I took sometime last year. Try to identify the three mystery organelles A through C And to be totally clear: A) The big blob in the lower right hand corner B) The dark round organelles…