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Alex Palazzo is a postdoctoral fellow working in the Department of Cell Biology at Harvard Medical School.

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June 30, 2006

Map That Campus IV

Category: Map that Campus

Can you tell me the identity of this week's mystery campus?

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Stochastic expression of proteins in a single cell

Category: Pure Biology

Every thought about how variable the expression of a particular gene is across an entire cell population? That's what the Weissman lab described in a manuscript in a recent issue of Nature. Anytime you want to take on such a...

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June 29, 2006

More Biology (Nerd) Rap

Category: Science & Society

First there was the Protein Synthesis Rap, now this ode to the animal kingdom. Enjoy....

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June 28, 2006

Being "Good at the Bench"

Category: Lab Life

Here's a tale from the lab. Today we had an interesting discussion. It started off with PBS and ended up on the topic of understanding the principles behind much of the protocols used in a lab. It all started when...

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June 27, 2006

Lazy Day Tuesday Morning Links

Category: Lab Life

Sciency links for you.

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June 26, 2006

I can't believe it

Category: World Cup 2006

... Italy last minute penalty. Goal. So was that "foul" worthy of a penalty shot? Was this a second game ruined by a bad ref? You tell me. All I know is that this victory for Gli Azzurri, left a...

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Giving your mRNA a boost by increasing GC content

Category: Pure Biology

Just read this Abstract from PLoS: Mammalian genes are highly heterogeneous with respect to their nucleotide composition, but the functional consequences of this heterogeneity are not clear. In the previous studies, weak positive or negative correlations have been found between...

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June 24, 2006

Get you very own Brazilian soccer name

Category: World Cup 2006

If you played for Brazil, what would your name be? Go to BrazilName to find out....

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Does technology make you happy?

Category: Science & Society

Lets think about technology for a moment. Here I am typing on this laptop. Ideas flow (misspelled and grammatically incorrect) from my brain to my fingers to the keyboard ... over a wireless network ... into the vast ethereal space (known as the internet) ... to your home/workplace/café. So what good is any of it? Does technology increase happiness?

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June 23, 2006

Map the Campus III

Category: Map that Campus

I provide the aerial photo and a hint, you tell me the mystery campus.

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Analysis of the US Performance in the World Cup

Category: World Cup 2006

A day after the US loss and I'm flabbergasted by the attention that the US team is getting. Soccer mania is spreading in the US, and I'm happy for it. It might be that unlike other areas (the Olympics, military might, world economic supremacy) soccer is hard. It's the happenin' party that the American public wants to attend, but just can't get invited to. It's that itch that is just a little too far to scratch. This is the sensation that turns bystanders into soccer nuts.

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June 22, 2006

NIH Funding Rates

Category: Lab Life

For those of you not in the biomedical sciences, you may not be aware of the coming crises. Right now aspiring postdocs and new independent investigators are involved in a war of attrition when it comes to funding. How did...

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June 21, 2006

RNA decay particles

Category: Pure Biology

There has been much fuss lately with p-bodies and the related structures termed "stress granules". Both structures are seen in most eukaryotes and play several seemingly incompatible roles. In general non-translating cytosolic mRNAs are shuffled into these structures. But why?

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Commenting at Cell

Category: Lab Life

Over the last month, many things have been happening in the world of scientific publishing. Nature is trying something new, and they are having a public debate about how to alter the review process. PLoS is pushing ahead with a...

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June 19, 2006

Free Online Science Seminars from AAAS

Category: Science & Society

I got this email from AAAS, and I thought I'd pass it along: Dear Colleague, We're now taking you behind the scenes of Science , presenting the authors of life science research papers in Science Online Seminars -- our compelling...

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Map that Campus II

Category: Map that Campus

It's time for another one. Can you figure out the mystery campus?

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June 18, 2006

Father's Day Entry

Category: Misc

What to write about? Immigration, Guantanamo, Father's Day, the Italian soccer team, war? Hmm ... well I have a good story for you then.

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June 17, 2006

Il Buono, il brutto, il cattivo

Category: World Cup 2006

Well if some Americans say soccer is boring, it's because they clearly weren't watch today's games. This group which was called by some the group of death (I guess all disputes about this title are resolved after today's games). So...

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World Cup Rundown

Category: World Cup 2006

For those Soccer Maniacs (or Futbolistas) here's my take on the first round of the World Cup ...

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June 15, 2006

Map that Campus I

Category: Map that Campus

I show you a satellite photo (courtesy of Google Maps) and give you a hint. You tell me what the mystery campus is.

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June 14, 2006

PLoS Blogs

Category: Lab Life

(via The Scientific Activist, Evolving Thoughts) First came PLoS, then PLoS ONE, now PLoS blogs A blog? Here's their mission: ... to give an insider's view of the latest developments at PLoS. To keep it simple, we've divided the content...

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Some comments on data and data reproduction.

Category: Lab Life

Part of the problem with Science is the verification process. From the outside looking in, you may guess that there is a quick and easy solution ... data should be reproduced by others. In the end scientists should be concerned...

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June 13, 2006

I Need More Hours in a Day

Category: Ask a ScienceBlogger

OK time for an irreverent answer to Scienceblog's question of the week.

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June 11, 2006

New Banners II

Category: Misc

OK still fiddling away with the banners. Here are the two latest ones: I've distributed the banners among the various sections (Latest Post, Individual Entries ...) I've also been advised that if I choose to have multiple banners, I should...

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New Banners

Category: Misc

I'm here at the lab. Watching the World Cup. Digesting DNA. Subclonning. And splicing in some new banners. Here are a couple of models: What do you think?...

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June 10, 2006

Soccernomics

Category: World Cup 2006

With regards to the World Cup, the Dutch Bank ABN AMRO has asked the question, "which team is our 'economic favourite', that is, the country which should become world champion in order to maximise the impact on the world economy."

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June 9, 2006

The Future is Rotting Plastic

Category: Pure Biology

Back in the fall of 2004, I submitted a prediction to TimeLine+25, a web based "cultural experiment" where random individuals were asked to predict near future events. Here was my entry for the year 2025: Plastic eating bacteria Novel forms...

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June 8, 2006

World Cup

Category: World Cup 2006

All I know is that there are many non-Americans around our department and this week the #1 topic of discussion is the upcoming World Cup. In the Longwood Medical Area there will be at least two spots that plan to show almost every game. In addition, the games will be shown at two local pubs - I have no clue how any of us will get any work done over the next month.

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A Review of Peer Review

Category: Lab Life

I was alerted to the fact that strange things are happening at Nature Magazine. From the Nature website: Peer review is the bedrock of scientific publication (for Nature's position on peer review, see our Guide to Authors). It is widely...

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June 7, 2006

Nature Publishing Group's Network Boston: A myspace site for scientists in the Boston Area

Category: Lab Life

Last night we were invited to celebrate the launching of Nature Publishing Group's Network Boston at the Museum of Science here in Boston. What, you may ask, is Network Boston? It was described as a new digital community center for...

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June 6, 2006

Rant on Technology

Category: Science & Society

OK here is a myth that I'd like to explode (or at least be provocative about). Technology is NOT inevitable. Say what? We humans think that technology increases steadily. With every space shuttle and iPod, humanity advances by one small...

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June 5, 2006

Lots of Links

Category: Misc

random stuff ...

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June 2, 2006

Cartoon Contest

Category: Science & Society

I just got this email from the Union of Concerned Scientists. Editorial Cartoon Contest Will Draw Attention to the Misuse and Abuse of Science Top Cartoonists Will Judge Amateur, Professional Talent in "Science Idol" WASHINGTON, DC - Teaming up with...

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News Tid Bits

Category: Education

Summers and the Allston expansion. Latest stats on gender and higher education. And free books! Ladies and Gentlemen start your hard drives.

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Read Happiness, Hear Happiness

Category: Science & Society

Well I've been engrossed in reading books on happiness, now apparently Bob McDonald from CBC's Quirks & Quarks interviews leading researchers in the field, including Dan Gilbert. (from Daily Zeitgeist) Previously: Last happiness entry. NY Times review of Stumbling On...

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June 1, 2006

Harold Varmus in WIRED

Category: Science & Society

Recently I've written a couple of entries on Journals and open access. In the latest WIRED, there's a good article on Harold Varmus, and his quest to shake up the biomedical journals. From the article: Varmus is the most visible...

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Protein Synthesis

Category: Misc

Yes it's a rap video of ... you guessed it....

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